ReviewThe Lancet regional health. Western Pacific2023
Tuberculosis in older adults: challenges and best practices in the Western Pacific Region.
Review in The Lancet regional health. Western Pacific, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Urban and rural prevalence of tuberculosis in low- and middle-income countries: A systematic review and meta-analysis.PLoS medicine · 2026Pooled it
- Tuberculosis epidemiology and programmatic progress in the WHO Western Pacific Region, 2010-2024: an analysis of surveillance data.Tropical medicine and health · 2026Article
- Factors Associated With Tuberculosis Treatment Failure Among Hill Tribe and Stateless People in Chiang Rai Province, Thailand: A Case-Control Study.Tropical medicine & international health : TM & IH · 2026Article
- Global, regional, and national tuberculosis burden associated with six suboptimal dietary exposures from 1990 to 2021: a comparative risk assessment based on the Global Burden of Disease Study 2021.Journal of thoracic disease · 2026Article
- Community-based chest X-ray screening versus symptom-based case presentation in the elderly: evidence from three consecutive years of data.BMC geriatrics · 2026Article
- Trends in incidence and DALYs of infectious disease from 2000 to 2023 and the attributable risk factors in China: an analysis of the Global Burden of Disease Study 2023.The Lancet regional health. Western Pacific · 2026Article
- Spatial heterogeneity and drivers of pulmonary tuberculosis in Guangzhou: a street-level analysis of residents and migrant subgroups from 2015 to 2023.BMC public health · 2026Article
- Elimination of senescent cells with senolytic drugs as adjunctive host-directed therapy reduces tuberculosis progression in mice.Nature communications · 2026Article
- Host immunosenescence compromisesAging · 2026Article
- Rural Residence and One-Person Households Are Associated with Diagnostic Delay in Pulmonary Tuberculosis in a Low-Incidence European Setting.Tropical medicine and infectious disease · 2026Article
- Asymptomatic tuberculosis in Japan: a 15-year national surveillance study, 2008-2022.The Lancet regional health. Western Pacific · 2026Article
- Knowledge, attitude, and practices of households toward tuberculosis transmission and early diagnosis.Scientific reports · 2026Article
- Epidemiological mapping of drug-susceptible and resistant tuberculosis in 30 WHO high-burden countries:Saudi medical journal · 2026Article
- A global analysis of patterns of tuberculosis exposure and transmission.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Optimizing Quality of Care for Elderly Tuberculosis Patients in Shanghai, China: Insights from Patient Cascade of Care and Patient Pathway Analysis.Tropical medicine and infectious disease · 2026Article
- Tuberculosis in older adults (≥ 65 years): Global trends, sex differences, and regional variations, 2000-2023.BMC geriatrics · 2026Article
- Tuberculosis: An Ongoing Global Threat.Advances in experimental medicine and biology · 2026Review
- Genital tuberculosis initially presenting as pyometra and progressing to miliary tuberculosis: A case report.Respiratory medicine case reports · 2026Article
- Development and internal validation of a frailty risk stratification model for older patients with spinal tuberculosis.Frontiers in medicine · 2026Article
- Clinical Indicators Distinguishing Pulmonary Tuberculosis from Community-Acquired Pneumonia in Older Adults: A Prospective Multicenter Study.Pathogens (Basel, Switzerland) · 2025Observational
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
The Western Pacific has one of the fastest-growing older adult populations globally, and tuberculosis (TB) remains one of the foremost infectious causes of disease and death in the region. Older adults are at higher risk of TB due to immunosenescence, comorbidities, and increased institutionalisation. Atypical symptoms and reduced access to health services may delay care-seeking and TB diagnosis, while co-morbidity and increased risk of adverse drug reactions complicate TB treatment. Post-TB sequelae and socioeconomic challenges may decrease the quality of life after TB treatment completion. Despite their high disease burden and special challenges, there is a lack of regionally coordinated policies and guidelines to manage TB among older adults. Routine TB screening at aged-care facilities, age-friendly infrastructure and services, awareness of atypical TB features, integration of TB and non-communicable diseases services, and person-centred approaches to treatment support could improve TB management among older adults. Addressing these challenges and adopting the best practices identified should inform policy formulation and implementation. Funding: This project was funded by 1) the World Health Organization Regional Office for the Western Pacific, with financial contributions from the Government of the Republic of Korea through the Korean Disease Control and Prevention Agency and the Government of Japan through the Ministry of Health, Labour and Welfare, and 2) NUS Start-up Grant. The funders had no role in the paper design, collection, analysis, and interpretation of data and in writing of the paper.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.