Evidence map›Paper›PMID 37546920›Full record

ArticlebioRxiv : the preprint server for biology2023

Pathogenic CANVAS (AAGGG)

Julia A Hisey, Elina A Radchenko, Silvia Ceschi, Anastasia Rastokina, Nicholas H Mandel, Ryan J McGinty, Gabriel Matos-Rodrigues, Alfredo Hernandez, André Nussenzweig, Sergei M Mirkin

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Julia A HiseyDepartment of Biology, Tufts University, Medford, MA 02155, USA.
Elina A RadchenkoDepartment of Biology, Tufts University, Medford, MA 02155, USA.
Silvia CeschiDepartment of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova 35131, Italy.
Anastasia RastokinaDepartment of Biology, Tufts University, Medford, MA 02155, USA.
Nicholas H MandelDepartment of Biology, Tufts University, Medford, MA 02155, USA.
Ryan J McGintyDepartment of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts, USA.
Gabriel Matos-RodriguesLaboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
Alfredo HernandezDepartment of Biology, Tufts University, Medford, MA 02155, USA.
André NussenzweigLaboratory of Genome Integrity, National Cancer Institute NIH, Bethesda, MD, USA.
Sergei M MirkinDepartment of Biology, Tufts University, Medford, MA 02155, USA.
Tufts University · USNational Human Genome Research Institute · USHarvard University · USUniversity of Padua · IT

Funding

NIGMS Equipment SupplementR35GM130322 · NIGMS · TUFTS UNIVERSITY MEDFORD · PI SERGEI MIRKIN · 2019 to 2026
$4.6M
NIGMS NIH HHS R35 GM130322
6 · The paper itself

Abstract

CANVAS is a recently characterized repeat expansion disease, most commonly caused by homozygous expansions of an intronic (A

Identifiers

PMID37546920
PMCPMC10402041
OpenAlexW4385310379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.