Evidence map›Paper›PMID 37546852›Full record

ArticlebioRxiv : the preprint server for biology2023

Gas vesicle-blood interactions enhance ultrasound imaging contrast.

Bill Ling, Jeong Hoon Ko, Benjamin Stordy, Yuwei Zhang, Tighe F Didden, Dina Malounda, Margaret B Swift, Warren C W Chan, Mikhail G Shapiro

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Bill LingDivision of Chemistry and Chemical Engineering, California Institute of Technology; Pasadena, CA 91125, USA.
Jeong Hoon KoDivision of Chemistry and Chemical Engineering, California Institute of Technology; Pasadena, CA 91125, USA.
Benjamin StordyInstitute of Biomedical Engineering, University of Toronto; Toronto, ON M5S 3G9, Canada.
Yuwei ZhangInstitute of Biomedical Engineering, University of Toronto; Toronto, ON M5S 3G9, Canada.
Tighe F DiddenDivision of Chemistry and Chemical Engineering, California Institute of Technology; Pasadena, CA 91125, USA.
Dina MaloundaDivision of Chemistry and Chemical Engineering, California Institute of Technology; Pasadena, CA 91125, USA.
Margaret B SwiftDivision of Chemistry and Chemical Engineering, California Institute of Technology; Pasadena, CA 91125, USA.
Warren C W ChanInstitute of Biomedical Engineering, University of Toronto; Toronto, ON M5S 3G9, Canada.
Mikhail G ShapiroDivision of Chemistry and Chemical Engineering, California Institute of Technology; Pasadena, CA 91125, USA.

Funding

PREDOCTORAL TRAINING IN BIOLOGY AND CHEMISTRYT32GM007616 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI STERNBERG, PAUL WARREN · 1985 to 2019
$22.9M
Biogenic Gas Nanostructures As Molecular Imaging Reporters For UltrasoundR01EB018975 · NIBIB · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI Mikhail Shapiro · 2014 to 2026
$5.9M
NIBIB NIH HHS R01 EB018975NIGMS NIH HHS T32 GM007616
6 · The paper itself

Abstract

Gas vesicles (GVs) are genetically encoded, air-filled protein nanostructures of broad interest for biomedical research and clinical applications, acting as imaging and therapeutic agents for ultrasound, magnetic resonance, and optical techniques. However, the biomedical applications of GVs as a systemically injectable nanomaterial have been hindered by a lack of understanding of GVs' interactions with blood components, which can significantly impact

Identifiers

PMID37546852
PMCPMC10402017

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.