Evidence map›Paper›PMID 37546730›Full record

ArticlebioRxiv : the preprint server for biology2025

Growth directions and stiffness across cell layers determine whether tissues stay smooth or buckle.

Avilash Singh Yadav, Lilan Hong, Patrick M Klees, Annamaria Kiss, Manuel Petit, Xi He, Iselle M Barrios, Michelle Heeney, Anabella Maria D Galang, Richard S Smith and 2 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 12 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Avilash Singh YadavWeill Institute for Cell and Molecular Biology and Section of Plant Biology, School of Integrative Plant Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0009-0005-5621-0650
Lilan HongInstitute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear Agricultural Sciences of Ministry of Agriculture and Zhejiang Province, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-8205-7534
Patrick M KleesWeill Institute for Cell and Molecular Biology and Section of Plant Biology, School of Integrative Plant Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0009-0002-4228-0509
Annamaria KissLaboratoire Reproduction et Développement des Plantes, Univ Lyon, ENS de Lyon, UCB Lyon, CNRS, INRAE, INRIA, F-69342 Lyon, France.ORCID 0000-0002-2547-4064
Manuel PetitLaboratoire Reproduction et Développement des Plantes, Univ Lyon, ENS de Lyon, UCB Lyon, CNRS, INRAE, INRIA, F-69342 Lyon, France.ORCID 0000-0002-3211-0066
Xi HeInstitute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear Agricultural Sciences of Ministry of Agriculture and Zhejiang Province, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0003-4268-1775
Iselle M BarriosWeill Institute for Cell and Molecular Biology and Section of Plant Biology, School of Integrative Plant Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-2202-1374
Michelle HeeneyWeill Institute for Cell and Molecular Biology and Section of Plant Biology, School of Integrative Plant Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-6734-0219
Anabella Maria D GalangWeill Institute for Cell and Molecular Biology and Section of Plant Biology, School of Integrative Plant Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-9245-0396
Richard S SmithThe John Innes Centre, Norwich NR4 7UH, UK.ORCID 0000-0001-9220-0787
Arezki BoudaoudLadHyX, Ecole Polytechnique, CNRS, IP Paris, 91128 Palaiseau Cedex, France.ORCID 0000-0002-2780-4717
Adrienne H K RoederWeill Institute for Cell and Molecular Biology and Section of Plant Biology, School of Integrative Plant Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-6685-2984
Cornell University · USUniversité Claude Bernard Lyon 1 · FRZheJiang Academy of Agricultural Sciences · CNCentre National de la Recherche Scientifique · FRJohn Innes Centre · GB

Funding

Mechanisms of robustness in organogenesis (Equipment Supplement 2023)R01GM134037 · NIGMS · CORNELL UNIVERSITY · PI ROEDER, ADRIENNE H · 2020 to 2023
$1.5M
NIGMS NIH HHS R01 GM134037
6 · The paper itself

Abstract

From smooth shapes to buckles, nature exhibits organs of various shapes and forms. How cells grow to produce smooth shaped leaves and sepals remain unclear. Here, we show that growth along the longitudinal axis during early developmental stages and comparable stiffness across both epidermal layers of Arabidopsis sepals are essential for smoothness, as seen in the wild type. We identified a mutant (

Identifiers

PMID37546730
PMCPMC10401922
OpenAlexW4385257357

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.