Evidence map›Paper›PMID 37546397›Full record

ReviewFrontiers in oncology2023

Radiotherapy plus immune checkpoint inhibitor in prostate cancer.

Tianjie Li, Xinye Qian, Jinyang Liu, Feng Xue, Jing Luo, Guanqun Yao, Jun Yan, Xiaodong Liu, Bo Xiao, Jianxing Li

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tianjie LiSchool of Clinical Medicine, Tsinghua University, Beijing, China.
Xinye QianSchool of Clinical Medicine, Tsinghua University, Beijing, China.
Jinyang LiuSchool of Medical, Tsinghua University, Beijing, China.
Feng XueSchool of Clinical Medicine, Tsinghua University, Beijing, China.
Jing LuoSchool of Clinical Medicine, Tsinghua University, Beijing, China.
Guanqun YaoSchool of Clinical Medicine, Tsinghua University, Beijing, China.
Jun YanSchool of Clinical Medicine, Tsinghua University, Beijing, China.
Xiaodong LiuDepartment of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Bo XiaoDepartment of Urology, Beijing Tsinghua Changung Hospital, Beijing, China.
Jianxing LiDepartment of Urology, Beijing Tsinghua Changung Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immune checkpoint inhibitor (ICI) is a promising strategy for treating cancer. However, the efficiency of ICI monotherapy is limited, which could be mainly attributed to the tumor microenvironment of the "cold" tumor. Prostate cancer, a type of "cold" cancer, is the most common cancer affecting men's health. Radiotherapy is regarded as one of the most effective prostate cancer treatments. In the era of immune therapy, the enhanced antigen presentation and immune cell infiltration caused by radiotherapy might boost the therapeutic efficacy of ICI. Here, the rationale of radiotherapy combined with ICI was reviewed. Also, the scheme of radiotherapy combined with immune checkpoint blockades was suggested as a potential option to improve the outcome of patients with prostate cancer.

Indexed as

cold tumorimmune checkpoint inhibitorprostate cancerradiotherapytoxicity

Identifiers

PMID37546397
PMCPMC10403272

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.