Evidence map›Paper›PMID 37546221›Full record

ReviewRSC advances2023

Benzophenones-natural metabolites with great Hopes in drug discovery: structures, occurrence, bioactivities, and biosynthesis.

Sabrin R M Ibrahim, Duaa Fahad ALsiyud, Abdulrahman Y Alfaeq, Shaimaa G A Mohamed, Gamal A Mohamed

Abstract readReview
In one paragraph

Review in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Journal of microbiology and biotechnology · 2025
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sabrin R M IbrahimPreparatory Year Program, Department of Chemistry, Batterjee Medical College Jeddah 21442 Saudi Arabia sabrin.ibrahim@bmc.edu.sa +966-581183034.ORCID https://orcid.org/0000-0002-6858-7560
Duaa Fahad ALsiyudDepartment of Medical Laboratories - Hematology, King Fahd Armed Forces Hospital Corniche Road, Andalus Jeddah 23311 Saudi Arabia duaaalsiyud@yahoo.com.
Abdulrahman Y AlfaeqPharmaceutical Care Department, Ministry of National Guard - Health Affairs Jeddah 22384 Saudi Arabia Faegab@mngha.med.sa.
Shaimaa G A MohamedFaculty of Dentistry, British University, El Sherouk City Suez Desert Road Cairo 11837 Egypt shaimaag1973@gmail.com.
Gamal A MohamedDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University Jeddah 21589 Saudi Arabia gahussein@kau.edu.sa.ORCID https://orcid.org/0000-0002-2971-6008

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungi have protruded with enormous development in the repository of drug discovery, making them some of the most attractive sources for the synthesis of bio-significant and structural novel metabolites. Benzophenones are structurally unique metabolites with phenol/carbonyl/phenol frameworks, that are separated from microbial and plant sources. They have drawn considerable interest from researchers due to their versatile building blocks and diversified bio-activities. The current work aimed to highlight the reported data on fungal benzophenones, including their structures, occurrence, and bioactivities in the period from 1963 to April 2023. Overall, 147 benzophenones derived from fungal source were listed in this work. Structure activity relationships of the benzophenones derivatives have been discussed. Also, in this review, a brief insight into their biosynthetic routes was presented. This work could shed light on the future research of benzophenones.

Identifiers

PMID37546221
PMCPMC10402873

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.