Evidence map›Paper›PMID 37546159›Full record

ArticleClinical case reports2023

Fasciotomy on a female patient with acquired factor VIII: A case report and literature review of management.

Katie Lovell, Bethlehem Peters, Melisa Pasli, Katie Kennedy, Darla Liles, Walter Pories

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katie LovellEast Carolina University Brody School of Medicine Greenville North Carolina USA.ORCID https://orcid.org/0009-0005-0098-8455
Bethlehem PetersEast Carolina University Brody School of Medicine Greenville North Carolina USA.
Melisa PasliEast Carolina University Brody School of Medicine Greenville North Carolina USA.
Katie KennedyDepartment of Hematology/Oncology ECU Health Brody School of Medicine Greenville North Carolina USA.
Darla LilesDepartment of Hematology/Oncology ECU Health Brody School of Medicine Greenville North Carolina USA.
Walter PoriesDepartment of Surgery ECU Health Brody School of Medicine Greenville North Carolina USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key Clinical Message: Acquired factor VIII inhibitors can be a rare cause of extensive intramuscular bleeding requiring fasciotomy. The subsequent postoperative period requires close monitoring due to high risk of fatal blood loss. Abstract: Acquired factor VIII inhibitors are a rare cause of often extensive bleeding and subsequently large hematomas. This disorder's overall mortality can reach 38%, largely due to immunosuppression and subsequent infections or an underlying cause such as malignancy. The patient in this case study presented with a hematoma and extensive ecchymosis of the hand and forearm, which continued to progress, precipitating compartment syndrome of the hand and forearm and ultimately requiring fasciotomy. The combination of factors led to significant blood loss in the postoperative period requiring major fluid resuscitation and intensive care unit (ICU) level care. Due to this disorder's rarity and overall mortality, we present this case report with a literature review for management of acquired hemophilia in the setting of urgent fasciotomy.

Indexed as

acquired hemophiliacompartment syndromefactor VIII inhibitorsfasciotomyhematologyimmunologysurgery

Identifiers

PMID37546159
PMCPMC10400796

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.