Evidence map›Paper›PMID 37545970›Full record

ArticleAfrican health sciences2023

A survey of chloroquine use for prevention and treatment of COVID-19 in Nigeria.

Adeola Yetunde Olukosi, Muinah Fowora, Adeniyi Kazeem Adeneye, Emelda Chukwu, Oluwagbemiga Aina, Olusola Ajibaye, Ayorinde James, Chidinma Gab-Okafor, Susan Abiodun Holdbrooke, Esther Ngozi Ohihoin and 6 more

Abstract read
In one paragraph

Article in African health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Adeola Yetunde OlukosiBiochemistry and Nutrition Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Muinah FoworaMolecular Biology and Biotechnology Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Adeniyi Kazeem AdeneyePublic Health and Epidemiology Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Emelda ChukwuMicrobiology Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Oluwagbemiga AinaBiochemistry and Nutrition Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Olusola AjibayeBiochemistry and Nutrition Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Ayorinde JamesBiochemistry and Nutrition Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Chidinma Gab-OkaforBiochemistry and Nutrition Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Susan Abiodun HoldbrookeBiochemistry and Nutrition Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Esther Ngozi OhihoinClinical Science Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Adesola Zaidat MusaMonitoring and Evaluation Unit, Nigerian Institute of Medical Research Yaba, Lagos. Nigeria.
Olufemi AmooMicrobiology Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Oluyomi ShowemimoObafemi Awolowo University, Ile Ife, Osun State, Nigeria.
Bamgboye AfolabiHealth, Environment and Development Foundation, Surulere, Lagos State, Nigeria.
Oliver Chukwujekwu EzechiClinical Science Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria.
Babatunde Lawal SalakoNigerian Institute of Medical Research, Yaba, Lagos, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rampant chloroquine/hydroxychloroquine poisoning in Nigerian hospitals following suggestions of its possible efficacy in the treatment and prevention of the newly emerged COVID-19 disease informed this survey. Objectives: The aim of this study was to assess the knowledge, attitude and perception of the Nigerian populace on the use of chloroquine in the COVID-19 pandemic. Methods: This cross-sectional study was done by administering an electronic questionnaire created using Google Docs, through social media cascade methods including the WhatsApp application software to capture data on chloroquine use between April 20 and June 20, 2020. Results: Six hundred and twenty-eight people responded to the questionnaire (response rate 99.2%, mean age 41.05 ± 12.3) from the six geopolitical zones in Nigeria with 556 (88.5%) having tertiary level education. Only 21 (3.3%) of the respondents took chloroquine for treatment or prevention. Respondents from the North-west geopolitical zones used chloroquine 5.8 (95% CI: 1.55, 21.52, p=0.02) more times than other zones while the age group 20-29 were 8.8 times more likely to use chloroquine than any other age group (95% CI: 3.53, 21.70, p = 0.00). Female respondents were 2.3 times more likely to use chloroquine than the males (OR 2.26 95% CI: 0.90-5.68; p=0.08) and those in the income bracket of N75,000-99,000, 2.5 times more than other income groups. Conclusion: Young adults, North-western geopolitical zone, and female gender should be target groups for education on rational chloroquine use. The danger of chloroquine overdose should be communicated to the general population in Nigeria.

Indexed as

COVID-19AdultChloroquineCOVID-19 Drug TreatmentCross-Sectional StudiesFemaleHumansMaleMiddle AgedNigeriaPandemicsSurveys and QuestionnairesYoung AdultChloroquineChloroquine/hydroxychloroquineCOVID-19rational drug useself-medication

Identifiers

PMID37545970
PMCPMC10398476

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.