Evidence map›Paper›PMID 37545947›Full record

ArticleAfrican health sciences2023

Clopidogrel-induced thrombotic thrombocytopenic purpura: a case report.

Chidozie N Ndulue, Nonyelum N Jisieike-Onuigbo, Nwabueze J Okwesa, Arinze Anyanor, Bartholomew C Ozuemba, Nwamaka Osakwe, Fidelis Oguejiofor, Hyacinth Eze, Anya Ofia Kalu, Charles U Odenigbo

Abstract readCase Reports
In one paragraph

Article in African health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Thrombotic thrombocytopaenic purpura.European heart journal. Case reports · 2025
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chidozie N NdulueDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Nonyelum N Jisieike-OnuigboDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Nwabueze J OkwesaDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Arinze AnyanorDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Bartholomew C OzuembaDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Nwamaka OsakweDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Fidelis OguejioforDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Hyacinth EzeDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Anya Ofia KaluDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.
Charles U OdenigboDepartment of Medicine, Nnamdi Azikiwe University Teaching Hospital Nnewi, Anambra State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombotic thrombocytopenic purpura (TTP) is a rare variant of thrombotic microangiopathy. We report a case of TTP in a Nigerian chronic kidney disease (CKD) patient who was previously on clopidogrel. The features of TTP resolved soon after clopidogrel was withdrawn. Clopidogrel is a cardio-protective anti-platelet drug used in CKD patients at risk of dyspepsia. However, its potential to cause TTP should be recognized and considered in acute kidney injury (AKI) patients previously on clopidogrel.

Indexed as

Purpura, Thrombotic ThrombocytopenicRenal Insufficiency, ChronicClopidogrelHumansPlatelet Aggregation InhibitorsTiclopidineClopidogrelPlatelet Aggregation InhibitorsTiclopidineAKICKDClopidogrelThrombotic Thrombocytopenic Purpurauremic encephalopathy

Identifiers

PMID37545947
PMCPMC10398446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.