ArticleWorld journal of stem cells2023
Injectable hydrogel made from antler mesenchyme matrix for regenerative wound healing
Article in World journal of stem cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Local and systemic factors both required for full renewal of deer antlers, and systemic factors only for generic cutaneous regenerative healing.Cell regeneration (London, England) · 2025Review
- Mesenchymal stem cells in wound healing: A bibliometric analysis as a powerful research tool.World journal of stem cells · 2024Article
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Authors and funding
7 authors.
Funding
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Abstract
backgroundScar formation and loss of cutaneous appendages are the greatest challenges in cutaneous wound healing. Previous studies have indicated that antler reserve mesenchyme (RM) cells and their conditioned medium improved regenerative wound healing with partial recovery of cutaneous appendages.
aimTo develop hydrogels from the antler RM matrix (HARM) and evaluate the effect on wound healing.
methodsWe prepared the hydrogels from the HARM
resultsThe results showed that HARM accelerated wound healing rate and reduced scar formation. Also, HARM stimulated the regeneration of cutaneous appendages and blood vessels, and reduced collagen fiber aggregation. Further study showed that these functions might be achieved
conclusionOverall, we successfully developed an injectable hydrogel made from antler RM matrix for the regenerative repair of full-thickness cutaneous wounds. We uncovered the molecular mechanism of the hydrogels in promoting regenerative wound healing, and thus pave the way for HARM to be developed for the clinic use.
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