Evidence map›Paper›PMID 37545725›Full record

ArticleFrontiers in neurology2023

High posterior cerebral artery flow predicts ischemia recurrence in patients with internal carotid artery occlusion.

Simon Jud, Robert Klövekorn, Christiaan Hendrik Bas van Niftrik, Lisa Herzog, Martina Sebök, Juliane Schweizer, Andreas R Luft, Jorn Fierstra, Susanne Wegener

Abstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simon JudDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Robert KlövekornDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Christiaan Hendrik Bas van NiftrikClinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Lisa HerzogDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Martina SebökClinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Juliane SchweizerDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Andreas R LuftDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Jorn FierstraClinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Susanne WegenerDepartment of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent stroke is a dreaded complication of symptomatic internal carotid artery occlusion (ICAO). Transcranial Duplex (TCD)-derived increased flow velocity in the ipsilateral posterior cerebral artery (PCA)-P2 segment indicates activated leptomeningeal collateral recruitment and hemodynamic impairment. Leptomeningeal collaterals are pial vascular connections between the anterior and posterior vascular territories. These secondary collateral routes are activated when primary collaterals via the Circle of Willis are insufficient. Our goal was to test the TCD parameter PCA-P2 flow for prediction of ipsilateral ischemia recurrence. We retrospectively analyzed clinical and ultrasound parameters in patients with ICAO. Together with clinical variables, we tested systolic PCA-P2 flow velocity as predictor of a recurrent ischemic event using logistic regression models. Of 111 patients, 13 showed a recurrent ischemic event within the same vascular territory. Increased flow in the ipsilateral PCA-P2 on transcranial ultrasound (median and interquartile range [IQR]: 60 cm/s [IQR 26] vs. 86 cm/s [IQR 41],

Indexed as

collateralsinternal carotid artery occlusionposterior cerebral arteryrecurrent stroketranscranial duplex

Identifiers

PMID37545725
PMCPMC10397388

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.