Evidence map›Paper›PMID 37545309›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2023

Multisensory integration in the mammalian brain: diversity and flexibility in health and disease.

Ilsong Choi, Ilayda Demir, Seungmi Oh, Seung-Hee Lee

Abstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  8. Review
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  11. Article
  12. Article
  13. Peripersonal space: why so last-second?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  14. Article
  15. Review
  16. Article
  17. How the brain controls decision making in a multisensory world.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ilsong ChoiCenter for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS), Daejeon 34141, Republic of Korea.
Ilayda DemirDepartment of biological sciences, KAIST, Daejeon 34141, Republic of Korea.
Seungmi OhDepartment of biological sciences, KAIST, Daejeon 34141, Republic of Korea.
Seung-Hee LeeCenter for Synaptic Brain Dysfunctions, Institute for Basic Science (IBS), Daejeon 34141, Republic of Korea.ORCID 0000-0002-9486-5771

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multisensory integration (MSI) occurs in a variety of brain areas, spanning cortical and subcortical regions. In traditional studies on sensory processing, the sensory cortices have been considered for processing sensory information in a modality-specific manner. The sensory cortices, however, send the information to other cortical and subcortical areas, including the higher association cortices and the other sensory cortices, where the multiple modality inputs converge and integrate to generate a meaningful percept. This integration process is neither simple nor fixed because these brain areas interact with each other via complicated circuits, which can be modulated by numerous internal and external conditions. As a result, dynamic MSI makes multisensory decisions flexible and adaptive in behaving animals. Impairments in MSI occur in many psychiatric disorders, which may result in an altered perception of the multisensory stimuli and an abnormal reaction to them. This review discusses the diversity and flexibility of MSI in mammals, including humans, primates and rodents, as well as the brain areas involved. It further explains how such flexibility influences perceptual experiences in behaving animals in both health and disease. This article is part of the theme issue 'Decision and control processes in multisensory perception'.

Indexed as

BrainBrain MappingAnimalsCognitionHumansMammalsPrimatesSensationautism spectrum disorderflexibilitymultisensory integrationschizophreniasensory processing

Identifiers

PMID37545309
PMCPMC10404930

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.