Evidence map›Paper›PMID 37545057›Full record

ArticleThoracic cancer2023

A case of discordant histology and expression of programmed death ligand 1 between primary tumor and brain metastases in adenosquamous carcinoma of the lung.

Hironori Takagi, Satoshi Muto, Akio Enta, Mitsuro Fukuhara, Shigeyuki Asano, Yutaka Shio, Hiroyuki Suzuki

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Thoracic cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hironori TakagiDepartment of Chest Surgery, Iwaki City Medical Center, Iwaki, Japan.ORCID 0000-0001-5438-2479
Satoshi MutoDepartment of Chest Surgery, Fukushima Medical University, Fukushima, Japan.
Akio EntaDepartment of Chest Surgery, Iwaki City Medical Center, Iwaki, Japan.
Mitsuro FukuharaDepartment of Chest Surgery, Iwaki City Medical Center, Iwaki, Japan.
Shigeyuki AsanoPathology Center, Iwaki City Medical Center, Iwaki, Japan.
Yutaka ShioDepartment of Chest Surgery, Fukushima Medical University, Fukushima, Japan.
Hiroyuki SuzukiDepartment of Chest Surgery, Fukushima Medical University, Fukushima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A patient presented with vomiting and gait disturbance. Investigation revealed a single cerebellar tumor and another tumor in the upper lobe of the left lung. Based on the severe vomiting and gait disturbance, we removed the cerebellar tumor first, achieving resolution of symptoms. The cerebellar tumor was pathologically diagnosed as metastatic lung adenocarcinoma. No other metastases were identified, including in the mediastinal lymph nodes. We therefore resected the primary lung tumor. On final pathological analysis, the tumor in the upper lobe of the left lung was diagnosed as adenosquamous carcinoma with no lymph node metastasis. PD-L1 expression was low in the primary lung adenosquamous carcinoma and high in the cerebellar metastasis. Furthermore, both tumors were KRAS

Indexed as

Brain NeoplasmsCarcinoma, AdenosquamousCerebellar NeoplasmsLung NeoplasmsB7-H1 AntigenBiomarkers, TumorHumansLungB7-H1 AntigenBiomarkers, TumorCD274 protein, humanadenosquamous carcinomaheterogeneitylung canceroligometastasisprogrammed death ligand 1 (PD-L1)

Identifiers

PMID37545057
PMCPMC10493479

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.