Evidence map›Paper›PMID 37544995›Full record

ArticleBMC infectious diseases2023

Candida auris Blood stream infection- a descriptive study from Qatar.

Junais Koleri, Hawabibee Mahir Petkar, Hussam Abdel Rahman S Al Soub, Muna A Rahman S AlMaslamani

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Blood Stream Infections due toInternational journal of microbiology · 2026
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  5. Risk factors associated withEpidemiology and infection · 2025
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  6. Article
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  8. Review
  9. The multidrug-resistantCurrent research in microbial sciences · 2025
    Review
  10. Annual review of medicine · 2025
    Review
  11. Article
  12. First report ofEmerging microbes & infections · 2024
    Article
  13. Antimicrobial agents and chemotherapy · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Emergence of highly resistantFrontiers in public health · 2023
    Article
  18. Detection ofAnnals of Saudi medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Junais KoleriDivision of Infectious Diseases, Hamad Medical Corporation, PO Box 3050, Doha, Qatar. JKoleri@hamad.qa.
Hawabibee Mahir PetkarDivision of Infectious Diseases, Hamad Medical Corporation, PO Box 3050, Doha, Qatar.
Hussam Abdel Rahman S Al SoubDivision of Infectious Diseases, Hamad Medical Corporation, PO Box 3050, Doha, Qatar.
Muna A Rahman S AlMaslamaniDivision of Infectious Diseases, Hamad Medical Corporation, PO Box 3050, Doha, Qatar.
Hamad Medical Corporation · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCandida auris is an emerging yeast pathogen that can cause invasive infections, particularly candidemia, in healthcare settings. Candida auris is characterized by resistance to multiple classes of antifungal drugs and high mortality.

objectiveTo describe the risk factors, clinical characteristics, antifungal susceptibility pattern and outcomes of Candida auris blood stream infection.

methodsWe conducted a retrospective review of electronic medical records of C. auris fungemia cases in the facilities under Hamad Medical corporation, Qatar from 1/11/2018 to 31/7/2021. Demographic data, risk factors, antibiogram and 30-day outcome are described.

resultsWe identified 36 patients with C. auris fungemia. Most of the patients were in intensive care unit following severe COVID-19 pneumonia and had received steroids and broad-spectrum antibiotics. Most cases were central line related. Over 90% of isolates were non-susceptible to fluconazole, while amphotericin B resistance reached 85%. Factors associated with high mortality included initial SOFA score of 9 or above and absence of source control.

conclusionOur study reveals a concerning 41.6% mortality rate within 30 days of C. auris candidemia. Furthermore, the prevalence of amphotericin B resistance in Qatar exceeds what has been reported in the literature necessitating further exploration. Echinocandins retains nearly 100% susceptibility and should be prioritized as the treatment of choice. These findings emphasize the need for vigilant monitoring and appropriate management strategies to combat C. auris infections and improve patient outcomes.

Indexed as

CandidemiaCOVID-19Amphotericin BAntifungal AgentsCandida aurisCandidiasis, InvasiveHumansMicrobial Sensitivity TestsQatarAmphotericin BAntifungal AgentsBlood stream infectionCandida aurisCandidemiaCOVID-19Fungemia

Identifiers

PMID37544995
PMCPMC10405369
OpenAlexW4385614698

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.