Evidence map›Paper›PMID 37544667›Full record

ArticleHarmful algae2023

Microcystin congeners in Lake Erie follow the seasonal pattern of nitrogen availability.

Justin D Chaffin, Judy A Westrick, Laura A Reitz, Thomas B Bridgeman

Open access · hybridAbstract read
In one paragraph

Article in Harmful algae, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Secondary metabolism ofApplied and environmental microbiology · 2026
    Review
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  20. Cool temperature acclimation in toxigenicbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Justin D ChaffinF.T. Stone Laboratory and Ohio Sea Grant, The Ohio State University, 878 Bayview Ave. P.O. Box 119, Put-In-Bay, OH 43456, USA. Electronic address: chaffin.46@osu.edu.
Judy A WestrickLumigen Instrument Center, Wayne State University, 5101 Cass Ave, Detroit, MI 48202, USA.
Laura A ReitzDepartment of Biological Sciences, Bowling Green State University, Life Sciences Building, Bowling Green, OH 43402, USA.
Thomas B BridgemanLake Erie Center, University of Toledo, Oregon, OH, 43416, USA.
Bowling Green State University · USOhio Sea Grant College Program · USUniversity of Toledo · USWayne State University · US

Funding

Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2014 to 2021
$10.1M
The synergistic effects of climate and anthropogenic drivers on toxic cyanobacterial bloomsP01ES028939 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gregory James Dick, David Joseph Kennedy · 2018 to 2026
$3.7M
NIEHS NIH HHS P01 ES028939NIEHS NIH HHS P30 ES020957
6 · The paper itself

Abstract

Cyanobacteria harmful algal blooms produce many toxic secondary metabolites called cyanotoxins. The most studied group of cyanotoxins are microcystins (MC), with over 300 congeners reported. MC-LR is the most studied congener because of its abundance and toxicity. Recent toxicology studies suggest that more hydrophobic MC congeners such as MC-LA, MC-LF, and MC-LW may be less abundant but up to seven times more toxic than MC-LR, whereas, MC-RR's toxicity is only one-fifth that of MC-LR. Hence, understanding the environmental stressors that change the MC congener profile is critical to assessing the negative impact on environmental and human health. A two-year field and experimental study investigated seasonal and spatial changes of MC congener profiles in the western basin of Lake Erie. Both studies showed that nitrogen enrichment favored the production of nitrogen-rich MC-RR (C

Indexed as

LakesMicrocystinsChromatography, LiquidCyanobacteria ToxinsHumansNitrogenSeasonsTandem Mass SpectrometryCyanobacteria ToxinsMicrocystinsNitrogenCyanobacteriaEutrophicationMicrocystisToxicity

Identifiers

PMID37544667
PMCPMC10867787
OpenAlexW4379056885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.