Evidence map›Paper›PMID 37544395›Full record

Trial reportBone2023

The association of vitamin D with bone microarchitecture, muscle strength, and mobility performance in older women in long-term care.

Nami Safai Haeri, Subashan Perera, Susan L Greenspan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Bone, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Role of vitamins in the development and treatment of osteoporosis (Review).International journal of molecular medicine · 2025
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nami Safai HaeriDivision of Geriatric Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: safaihaerin@upmc.edu.
Subashan PereraDivision of Geriatric Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA.
Susan L GreenspanDivision of Geriatric Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
Maintenance of Skeletal Integrity in Frail Elders-Phase 2R01AG050302 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GREENSPAN, SUSAN L · 2015 to 2019
$3.0M
Long-Term Care Research NetworkK07AG052668 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GREENSPAN, SUSAN L · 2016 to 2020
$439k
NIA NIH HHS K07 AG052668NIA NIH HHS P30 AG024827NIA NIH HHS R01 AG050302NIA NIH HHS T32 AG021885
6 · The paper itself

Abstract

backgroundOsteoporosis and sarcopenia are prevalent in older adults. Trabecular bone score (TBS) is a novel method to evaluate bone microarchitecture, whereas grip strength and gait speed are simple methods to assess muscle strength and function. Few studies have linked the relationship between vitamin D levels (25OHD) with TBS, grip strength, and gait speed in healthy community dwelling adults. We sought to investigate this relationship in older women with osteoporosis and multiple comorbid conditions residing in long-term care (LTC) facilities.

methodsWe analyzed baseline 25OHD, spine TBS, grip strength, and gait speed in 246 women with osteoporosis who were residents of LTC and enrolled in a randomized controlled clinical trial.

resultsOn average, participants were 81.6 years old and had a BMI of 26.8 kg/m

conclusionIn older women residing in LTC facilities, 25OHD was associated with spine TBS and gait speed. The strengths of the associations suggest there may be other factors with a more prominent role in bone microarchitecture, muscle strength, and physical function in this population. MINI ABSTRACT: Our study found in older women who are residents of long-term care facilities, vitamin D level is associated with bone microarchitecture and mobility performance.

Indexed as

OsteoporosisVitamin DAgedAged, 80 and overBone DensityFemaleHand StrengthHumansLong-Term CareMuscle StrengthVitaminsVitamin DVitamins25-Hydroxy vitamin DBone microarchitectureLong-term careMuscle strengthPhysical performance

Identifiers

PMID37544395
PMCPMC10528338

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.