Evidence map›Paper›PMID 37544044›Full record

ArticleVirology2023

Prevalence and characterization of seven-segmented influenza viruses in bovine respiratory disease complex.

Tirth Uprety, Chithra C Sreenivasan, Milton Thomas, Ben Hause, Jane Christopher-Hennings, Dale Miskimis, Angela Pillatzki, Eric Nelson, Dan Wang, Feng Li

Open access · greenAbstract read
In one paragraph

Article in Virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Sparse Evidence of Influenza C on US Dairy and Beef Cattle Farms.Influenza and other respiratory viruses · 2025
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tirth UpretyMaxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, 40546, USA.
Chithra C SreenivasanMaxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, 40546, USA.
Milton ThomasDepartment of Veterinary and Biomedical Science, South Dakota State University, Brookings, SD, 57007, USA.
Ben HauseDepartment of Veterinary and Biomedical Science, South Dakota State University, Brookings, SD, 57007, USA.
Jane Christopher-HenningsDepartment of Veterinary and Biomedical Science, South Dakota State University, Brookings, SD, 57007, USA.
Dale MiskimisDepartment of Veterinary and Biomedical Science, South Dakota State University, Brookings, SD, 57007, USA.
Angela PillatzkiDepartment of Veterinary and Biomedical Science, South Dakota State University, Brookings, SD, 57007, USA.
Eric NelsonDepartment of Veterinary and Biomedical Science, South Dakota State University, Brookings, SD, 57007, USA.
Dan WangMaxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, 40546, USA. Electronic address: dan.wang@uky.edu.
Feng LiMaxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, 40546, USA. Electronic address: Feng.Li@uky.edu.
South Dakota State University · USUniversity of Kentucky · US

Funding

Influenza D Virus Entry and Tissue TropismR01AI141889 · NIAID · UNIVERSITY OF KENTUCKY · PI LI, FENG · 2018 to 2022
$2.6M
NIAID NIH HHS R01 AI141889
6 · The paper itself

Abstract

Bovine respiratory disease (BRD) complex is a multifactorial respiratory disease of cattle. Seven-segmented influenza C (ICV) and D (IDV) viruses have been identified in cattle with BRD, however, molecular epidemiology and prevalence of IDV and ICV in the diseased population remain poorly characterized. Here, we conducted a molecular screening of 208 lung samples of bovine pneumonia cases for the presence of IDV and ICV. Our results demonstrated that both viruses were prevalent in BRD cases and the overall positivity rates of IDV and ICV were 20.88% and 5.99% respectively. Further analysis of three IDV strains isolated from lungs of cattle with BRD showed that these lung-tropic strains belonged to D/Michigan/2019 clade and diverged antigenically from the circulating dominant IDV clades D/OK and D/660. Our results reveal that IDV and ICV are associated with BRD complex and support a role for IDV and ICV in the etiology of BRD.

Indexed as

Bovine Respiratory Disease ComplexCattle DiseasesOrthomyxoviridaeOrthomyxoviridae InfectionsThogotovirusVirusesAnimalsCattlePrevalenceBovine respiratory diseaseCattleInfluenza C virusInfluenza D virus

Identifiers

PMID37544044
PMCPMC10592214
OpenAlexW4385543895

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.