Evidence map›Paper›PMID 37543908›Full record

ArticleArchives of Iranian medicine2022

Iron Oxide Nanoparticles Conjugated to Thiosemicarbazone Reduce the Survival of Cancer Cells by Increasing the Gene Expression of

Alireza Habibi, Nesa Bakhshi, Zeinab Moradi Shoili, Nour Amirmozafari

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of Iranian medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Alireza HabibiDepartman of Basic Sciences, Faculty of Science, Imam Hossein University, Tehran, Iran.ORCID 0000-0002-3672-5869
Nesa BakhshiDepartman of Molecular Cell Biology, Faculty of Science, Islamic Azad University of Lahijan, Lahijan, Iran.
Zeinab Moradi ShoiliDepartman of Chemistry, Faculty of Science, University of Guilan, Rasht, Iran.
Nour AmirmozafariDepartman of Microbiology, School of Medicine, University of Medical Sciences, Tehran, Iran.ORCID 0000-0001-5186-8406
Imam Hossein University · IRIslamic Azad University, Lahijan Branch · IRTehran University of Medical Sciences · IRUniversity of Guilan · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer cells have a higher demand for iron to grow and proliferate. A new complex of iron nanoparticles and thiosemicarbazones was synthesized. Confirmation tests included UV-visible, scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), Fourier transform infrared (FTIR), X-ray diffraction (XRD) and zeta potential.

methodsMTT assay, flow cytometry and qRT-PCR were used to investigate anti-proliferative effect, amount of apoptosis and the effect of Fe

resultsFe3O4@Glu/BTSC was more effective than BTSC and Fe

conclusionFe

Indexed as

Lung NeoplasmsMicroRNAsThiosemicarbazonesA549 CellsGene ExpressionHumansIronMagnetic Iron Oxide NanoparticlesIronMicroRNAsThiosemicarbazonesA549 cellsApoptosisFe3 O4 @Glu/ BTSCLung cancerMicroRNA let-7c

Identifiers

PMID37543908
PMCPMC10685841
OpenAlexW4366211157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.