Evidence map›Paper›PMID 37543652›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2023

Association of delivery risk phenotype with early-onset sepsis in preterm infants.

Sarah A Coggins, Sagori Mukhopadhyay, Jourdan Triebwasser, Kevin J Downes, Jason D Christie, Karen M Puopolo

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sarah A CogginsDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA. cogginss@chop.edu.ORCID http://orcid.org/0000-0003-3938-6337
Sagori MukhopadhyayDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-5851-8414
Jourdan TriebwasserDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.
Kevin J DownesDepartment of Pediatrics, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-5015-8146
Jason D ChristieDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
Karen M PuopoloDivision of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Children's Hospital of Philadelphia · USUniversity of Michigan · USUniversity of Pennsylvania · US

Funding

Cardiology & pulmonary research training grantT32HL007891 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI Jason D Christie · 1998 to 2026
$12.0M
Mentored Patient Oriented Research in Lung TransplantationK24HL115354 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI CHRISTIE, JASON D · 2012 to 2021
$1.2M
Optimizing Vancomycin Therapy in ChildrenK23HD091365 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI DOWNES, KEVIN JAMES · 2018 to 2022
$747k
NHLBI NIH HHS K24 HL115354NHLBI NIH HHS T32 HL007891NICHD NIH HHS K23 HD091365
6 · The paper itself

Abstract

objectiveTo determine delivery risk phenotype-specific incidence of early-onset sepsis (EOS) among preterm infants. STUDY

designRetrospective cohort study of infants born <35 weeks' gestation at four perinatal centers during 2017-2021. Infants were classified into one of six delivery risk phenotypes incorporating delivery mode, presence of labor, and duration of rupture of membranes (ROM). The primary outcome was EOS incidence within the overall cohort and each risk phenotype.

resultsAmong 2937 preterm infants, 21 had EOS (0.7%, or 7.1 cases/1000 preterm infants). The majority of EOS cases (13/21, 62%) occurred in the setting of prolonged ROM ≥ 18 h, with a phenotype incidence of 23.8 cases/1000 preterm infants. There were no EOS cases among infants born by cesarean section without ROM (with or without labor), nor via cesarean section with ROM < 18 h without labor.

conclusionDelivery risk phenotyping may inform EOS risk stratification in preterm infants.

Indexed as

Premature Rupture of Fetal MembranesSepsisCesarean SectionFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematurePregnancyRetrospective Studies

Identifiers

PMID37543652
PMCPMC10530160
OpenAlexW4385602265

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.