ArticlePsychiatry research2023
Relationship of stress-reactive cortisol to suicidal intent of prior attempts in major depression.
Article in Psychiatry research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Cortisol levels and depression suicide risk: a combined exploration of meta-analysis and case-control study.Frontiers in psychiatry · 2025Pooled it
- Physiological responses to acute psychological stress as a biomarker for depression: A systematic review and meta-analysis.Psychological bulletinPooled it
- Stress-related salivary biomarkers - cortisol, dehydroepiandrosterone, alpha amylase, and suicidal ideation among young women living in Kampala's informal settlements.Social psychiatry and psychiatric epidemiology · 2026Article
- Pursuing the elusive biosignature for suicide: a decennial update.Molecular psychiatry · 2026Review
- Sex differences in resting-state hypothalamic connectivity and its relationship with negative emotion and behavior measures in young adults.Brain structure & function · 2026Article
- Hair cortisol concentrations as a putative biomarker for suicidal behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Evaluating the Safety Profile of Glucagon-Like Peptide-1 Receptor Agonists: Adverse Events and Clinical Recommendations.Journal of obesity & metabolic syndrome · 2026Review
- Effects of Cyberball on cognitive vulnerability for suicide in youth with a history of multiple suicide attempts.Frontiers in psychiatry · 2026Article
- Hair stress hormones in individuals with a recent suicide attempt experiencing a depressive episode.Neurobiology of stress · 2026Article
- Neuroendocrine abnormalities as predictors of suicidal ideation in bipolar disorder patients during depressive episodes: a cross-sectional study.BMC psychiatry · 2025Article
- Physiological and cognitive reactivity to social exclusion among emerging adults with versus without a suicide attempt history.Psychiatry research communications · 2025Article
- Evaluation of peri-implant health and whole salivary cortisol levels in adults with mental health disorders.Scientific reports · 2025Article
- Do Cortisol Levels Play a Role in Suicidal Behaviors and Non-Suicidal Self-Injuries in Children and Adolescents?-A Narrative Review.Brain sciences · 2025Review
- Influences of sleep, cortisol reactivity, and risk/reward-based decision-making on suicide.Journal of behavior therapy and experimental psychiatry · 2024Article
- Research progress on antidepressant effects and mechanisms of berberine.Frontiers in pharmacology · 2024Review
- Searching for diagnoses and subgroups: a suggestion for criteria.Frontiers in psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Higher intent suicide attempts carry elevated risk of future suicidal behavior. Abnormal functioning of the hypothalamic-pituitary-adrenal (HPA) axis is both linked to nonfatal suicidal behavior and suicide deaths in major depressive disorder. Few studies, however, have identified biological markers of a high-intent suicidal subgroup. We examined HPA axis output and reactivity to the Trier Social Stress Test (TSST) via salivary cortisol in depressed individuals (N=68) with a suicide attempt (SA) history. A median split of higher and lower suicidal intent scores was used to define groups. Individuals with high intent SA had attenuated total cortisol output (AUC
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.