Evidence map›Paper›PMID 37542639›Full record

Trial reportOdontology2024

Clinical performance comparison between lithium disilicate and hybrid resin nano-ceramic CAD/CAM onlay restorations: a two-year randomized clinical split-mouth study.

Amr Hassan, Kareem Hamdi, Ashraf I Ali, Walid Al-Zordk, Salah Hasab Mahmoud

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Odontology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07648485 (Clinical Performance of CAD/CAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07648485 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Clinical Performance of CAD/CAM Hard Hybrid Ceramic Inlays Versus Resin Composite Inlays in Vital Molars With Extensive Occluso-Proximal Cavities: Two-Year Randomized Clinical Trial

TypeinterventionalSponsorCairo UniversityRan2026 to 2028Enrolled50ConditionsDental Caries, Cavity, Dental, Proximal Dental CariesArmshybrid ceramics, Composite resin
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Survival and Complications of Partial Coverage Restorations on Posterior Teeth-A Systematic Review and Meta-Analysis.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Pooled it
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  5. Trial
  6. Article
  7. Article
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  13. Review
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  15. Survival of Partial Coverage Restorations on Posterior Teeth-A Scoping Review.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Article
  16. Advances in Dental Restorations: A Comprehensive Review of Machinable and 3D-Printed Ceramic-Reinforced Composites.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amr HassanOperative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Kareem HamdiOperative Dentistry Department, Faculty of Dentistry, Zagazig University, Zagazig, Egypt. Kahamdy@dent.zu.edu.eg.ORCID http://orcid.org/0000-0002-6432-7438
Ashraf I AliOperative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Walid Al-ZordkFixed Prosthodontics Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Salah Hasab MahmoudOperative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
Mansoura University · EGDamietta University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A total of 20 lithium disilicate glass-ceramics (IPS e.max CAD, Ivoclar Vivadent) and 20 resin nano-ceramic (Voco Grandio Blocks) onlay restorations were performed in 20 patients using a split-mouth design to compare the two-year clinical performance of lithium disilicate and resin nano-ceramic onlay restorations. Both restorations were evaluated at baseline, one-year, and two-year clinical follow-ups based on the modified United States Public Health Service (USPHS) criteria. Chi-square and Fisher's exact tests showed no statistically significant difference between Voco Grandio and IPS e.max ceramic restorations for all evaluated parameters during the different follow-up periods (p > 0.05). Cochrane's and MC-Nemar's tests indicated statistically significant differences regarding color match within the Voco Grandio group. They also indicated statistically significant differences in marginal discoloration, marginal adaptation, surface texture, and postoperative hypersensitivity within both ceramic material groups (p < 0.05). Kaplan-Meier curve indicated that the survival rate of both ceramic materials was 90%. After two years of clinical service, IPS e.max CAD and Voco Grandio onlay restorations exhibited similar clinical performance.

Indexed as

CeramicsDental PorcelainComputer-Aided DesignHumansInlaysMaterials TestingMouthDental Porcelainlithia disilicateHybrid ceramicIndirect ceramic restorationsIPS e.maxLithium disilicateOnlaysPartial coverageResin nano-ceramic

Identifiers

PMID37542639
PMCPMC10925567
OpenAlexW4385597041

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.