Evidence map›Paper›PMID 37542573›Full record

ArticleSurgical and radiologic anatomy : SRA2023

Combined cone-beam CT imaging and microsurgical dissection of cadaver specimens to study cerebral venous anatomy: a technical note.

Markus E Krogager, Rasmus H Dahl, Lars Poulsgaard, Kåre Fugleholm, Tom Sehested, Ronni Mikkelsen, Jørgen Tranum-Jensen, Tiit I Mathiesen, Goetz Benndorf

Open access · hybridAbstract read
In one paragraph

Article in Surgical and radiologic anatomy : SRA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Markus E Krogager *Department of Neurosurgery, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark. markus.engebaek.krogager@regionh.dk.ORCID http://orcid.org/0000-0001-6393-2698
Rasmus H Dahl *Department of Radiology, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-2014-7400
Lars PoulsgaardDepartment of Neurosurgery, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-1506-5726
Kåre FugleholmDepartment of Neurosurgery, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-1520-7122
Tom SehestedDepartment of Neurosurgery, Aarhus University Hospital, Aarhus, Denmark.
Ronni MikkelsenDepartment of Neuroradiology, Aarhus University Hospital, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-0010-5123
Jørgen Tranum-JensenDepartment of Cellular and Molecular Medicine, The Panum Institute, University of Copenhagen, Copenhagen, Denmark.
Tiit I MathiesenDepartment of Neurosurgery, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0001-9463-1919
Goetz BenndorfDepartment of Radiology, University Hospital of Copenhagen, Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-9824-6900
Copenhagen University Hospital · DKUniversity of Copenhagen · DKAarhus University · DKAarhus University Hospital · DKBaylor College of Medicine · USHvidovre Hospital · DK

Funding

Fonden til Lægevidenskabens Fremme 20-L-0222
6 · The paper itself

Abstract

purposeCadaver dissections and X-ray based 3D angiography are considered gold standards for studying neurovascular anatomy. We sought to develop a model that utilize the combination of both these techniques to improve current tools for anatomical research, teaching and preoperative surgical planning, particularly addressing the venous system of the brain. MATERIALS AND

methodsSeven ethanol-fixed human cadaveric heads and one arm were injected with a latex-barium mixture into the internal jugular veins and the brachial artery. After the ethanol-based fixation, specimens were scanned by high-resolution cone-beam CT and images were post-processed on a 3D-workstation. Subsequent, microsurgical dissections were performed by an experienced neurosurgeon and venous anatomy was compared with relevant 3D venograms.

resultsLatex-barium mixtures resulted in a homogenous cast with filling of the cerebral venous structures down to 150 μm in diameter. The ethanol-based preparation of the cadaveric brains allowed for near-realistic microsurgical maneuverability during dissection. The model improves assessment of the venous system for anatomical education and hands-on surgical training.

conclusionTo our knowledge we describe the first preparation method which combines near-realistic microsurgical dissection of human heads with high-resolution 3D imaging of the cerebral venous system in the same specimens.

Indexed as

LatexTomography, X-Ray ComputedBariumCadaverCone-Beam Computed TomographyHumansBariumLatexBariumCadaverLatexNeuroanatomyNeuroradiologyVeins

Identifiers

PMID37542573
PMCPMC10514096
OpenAlexW4385597053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.