Evidence map›Paper›PMID 37542477›Full record

ArticleEuropean heart journal. Cardiovascular Imaging2023

Phenotyping heart failure by echocardiography: imaging of ventricular function and haemodynamics at rest and exercise.

Otto A Smiseth, Erwan Donal, Espen Boe, Jong-Won Ha, Joao F Fernandes, Pablo Lamata

Open access · hybridAbstract read
In one paragraph

Article in European heart journal. Cardiovascular Imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

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  12. Imaging-based method to quantify left ventricular diastolic pressures.European heart journal. Cardiovascular Imaging · 2025
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  17. Focus issue on heart failure with preserved left ventricular ejection fraction.European heart journal. Cardiovascular Imaging · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Otto A SmisethDivision of Cardiovascular and Pulmonary Diseases, Institute for Surgical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.ORCID 0000-0003-3005-9954
Erwan DonalDepartment of Cardiology, CHU Rennes and Inserm, LTSI, University of Rennes, Rennes, France.ORCID 0000-0003-2677-3389
Espen BoeDepartment of Cardiology, Oslo University Hospital, Rikshospitalet, Sognsvannsveien 20, Oslo, Norway.
Jong-Won HaDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
Joao F FernandesDepartment of Biomedical Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
Pablo LamataDepartment of Biomedical Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.ORCID 0000-0002-3097-4928
King's College London · GBOslo University Hospital · NOInserm · FRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditionally, congestive heart failure (HF) was phenotyped by echocardiography or other imaging techniques according to left ventricular (LV) ejection fraction (LVEF). The more recent echocardiographic modality speckle tracking strain is complementary to LVEF, as it is more sensitive to diagnose mild systolic dysfunction. Furthermore, when LV systolic dysfunction is associated with a small, hypertrophic ventricle, EF is often normal or supernormal, whereas LV global longitudinal strain can reveal reduced contractility. In addition, segmental strain patterns may be used to identify specific cardiomyopathies, which in some cases can be treated with patient-specific medicine. In HF with preserved EF (HFpEF), a diagnostic hallmark is elevated LV filling pressure, which can be diagnosed with good accuracy by applying a set of echocardiographic parameters. Patients with HFpEF often have normal filling pressure at rest, and a non-invasive or invasive diastolic stress test may be used to identify abnormal elevation of filling pressure during exercise. The novel parameter LV work index, which incorporates afterload, is a promising tool for quantification of LV contractile function and efficiency. Another novel modality is shear wave imaging for diagnosing stiff ventricles, but clinical utility remains to be determined. In conclusion, echocardiographic imaging of cardiac function should include LV strain as a supplementary method to LVEF. Echocardiographic parameters can identify elevated LV filling pressure with good accuracy and may be applied in the diagnostic workup of patients suspected of HFpEF.

Indexed as

Heart FailureVentricular Dysfunction, LeftEchocardiographyHemodynamicsHumansStroke VolumeVentricular Function, Leftdiastolic functiondigital twinechocardiographyheart failureleft ventricular ejection fractionstrain imagingsystolic function

Identifiers

PMID37542477
PMCPMC10531125
OpenAlexW4385602405

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.