Evidence map›Paper›PMID 37542319›Full record

ArticleBMC medicine2023

New tuberculosis vaccines in India: modelling the potential health and economic impacts of adolescent/adult vaccination with M72/AS01

Rebecca A Clark, Chathika K Weerasuriya, Allison Portnoy, Christinah Mukandavire, Matthew Quaife, Roel Bakker, Danny Scarponi, Rebecca C Harris, Kirankumar Rade, Sanjay Kumar Mattoo and 3 more

Open access · goldAbstract read
In one paragraph

Article in BMC medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 4 countries.

Rebecca A ClarkTB Modelling Group and TB Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. Rebecca.Clark@lshtm.ac.uk.ORCID http://orcid.org/0000-0001-8923-0301
Chathika K WeerasuriyaTB Modelling Group and TB Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Allison PortnoyCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, USA.
Christinah MukandavireTB Modelling Group and TB Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Matthew QuaifeTB Modelling Group and TB Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Roel BakkerTB Modelling Group and TB Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Danny ScarponiTB Modelling Group and TB Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Rebecca C HarrisTB Modelling Group and TB Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.
Kirankumar RadeWorld Health Organization, New Delhi, India.
Sanjay Kumar MattooCentral TB Division, NTEP, MoHFW Govt of India, New Delhi, India.
Dheeraj TumuWorld Health Organization, New Delhi, India.
Nicolas A MenziesCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, USA.
Richard G WhiteTB Modelling Group and TB Centre, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.ORCID https://orcid.org/0000-0003-4410-6635
University of London · GBWorld Health Organization - India · INBoston University · USHarvard Global Health Institute · US

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundIndia had an estimated 2.9 million tuberculosis cases and 506 thousand deaths in 2021. Novel vaccines effective in adolescents and adults could reduce this burden. M72/AS01

methodsWe developed an age-stratified compartmental tuberculosis transmission model for India calibrated to country-specific epidemiology. We projected baseline epidemiology to 2050 assuming no-new-vaccine introduction, and M72/AS01

resultsM72/AS01

conclusionsM72/AS01

Indexed as

Mycobacterium tuberculosisTuberculosisTuberculosis VaccinesAdolescentAdultBCG VaccineHumansImmunization, SecondaryIndiaVaccinationBCG VaccineTuberculosis VaccinesBudget impactCost-effectivenessHealth impactMathematical modellingTuberculosisVaccines

Identifiers

PMID37542319
PMCPMC10403932
OpenAlexW4385575173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.