Evidence map›Paper›PMID 37542225›Full record

ArticleBMC geriatrics2023

Incidence and risk factors for polypharmacy among elderly people assisted by primary health care in Brazil.

Andréia Mascarelo, Ana Luisa Sant'Anna Alves, Siomara Regina Hahn, Marlene Doring, Marilene Rodrigues Portella

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Andréia MascareloPostgraduate Program in Human Aging, University of Passo Fundo/UPF, BR 285 Km 292,7, Campus I, Bairro São José, Passo Fundo, RS, CEP 99052-900, Brazil. andreiamascarelo@yahoo.com.br.ORCID http://orcid.org/0000-0001-5424-8800
Ana Luisa Sant'Anna AlvesPostgraduate Program in Human Aging, University of Passo Fundo/UPF, BR 285 Km 292,7, Campus I, Bairro São José, Passo Fundo, RS, CEP 99052-900, Brazil.
Siomara Regina HahnPostgraduate Program in Human Aging, University of Passo Fundo/UPF, BR 285 Km 292,7, Campus I, Bairro São José, Passo Fundo, RS, CEP 99052-900, Brazil.
Marlene DoringPostgraduate Program in Human Aging, University of Passo Fundo/UPF, BR 285 Km 292,7, Campus I, Bairro São José, Passo Fundo, RS, CEP 99052-900, Brazil.
Marilene Rodrigues PortellaPostgraduate Program in Human Aging, University of Passo Fundo/UPF, BR 285 Km 292,7, Campus I, Bairro São José, Passo Fundo, RS, CEP 99052-900, Brazil.
Universidade de Passo Fundo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolypharmacy is recognized as a global public health problem and one of the greatest challenges related to the aging population. Few studies have investigated the incidence and risk factors for polypharmacy among elderly individuals. These studies provided important information on the issue but were developed in high-income countries. This study investigates the incidence and risk factors for polypharmacy among elderly people assisted by primary health care over a period of 11 years.

methodsThis was a census-based prospective longitudinal study that included people aged 60 years or older living in a small municipality in the state of Rio Grande do Sul, Brazil. The baseline occurred in 2010 and the second wave of the study occurred in 2021. The study population consisted of elderly individuals who did not use polypharmacy at baseline and were reinterviewed in 2021 (N = 128). Data collection in the first and second waves was performed through a household survey using a structured questionnaire. The dependent variable was polypharmacy, defined as the simultaneous use of 5 or more drugs. The independent variables included sociodemographic, health and functionality factors. For multivariate analyses, Poisson regression with robust variance was used, estimating the relative risk and 95% confidence intervals.

resultsThe incidence of polypharmacy was 46.1% in the 11-year period. The highest number of health problems was a risk factor for polypharmacy (RR = 1.177; 95% CI 1.093-1.267).

conclusionsThe incidence of polypharmacy among elderly people assisted in primary health care in Brazil is high. The number of diseases is a risk factor for polypharmacy. These results have implications for future primary health care practices and may support the development of policies, actions and services aimed at reducing polypharmacy and promoting the rational use of drugs in the population at higher risk.

Indexed as

PolypharmacyPrimary Health CareAgedBrazilHumansIncidenceLongitudinal StudiesProspective StudiesRisk FactorsAgedPolypharmacyPrimary health care

Identifiers

PMID37542225
PMCPMC10403929
OpenAlexW4385610931

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.