Evidence map›Paper›PMID 37542186›Full record

ReviewAnnals of intensive care2023

The impact of age-related syndromes on ICU process and outcomes in very old patients.

Hélène Vallet, Bertrand Guidet, Ariane Boumendil, Dylan W De Lange, Susannah Leaver, Wojciech Szczeklik, Christian Jung, Sigal Sviri, Michael Beil, Hans Flaatten

Open access · goldAbstract readReview
In one paragraph

Review in Annals of intensive care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 7 countries.

Hélène ValletInstitut National de la Santé et de la Recherche Médicale (INSERM), UMRS 1135, Centre d'immunologie et de Maladies Infectieuses (CIMI), Department of Geriatrics, Saint Antoine, Assistance Publique Hôpitaux de Paris (AP-HP), Sorbonne Université, F75012, Paris, France.
Bertrand GuidetInstitut Pierre Louis d'Epidémiologie et de Santé Publique, Hôpital Saint-Antoine, service de réanimation, Sorbonne Université, INSERM, AP-HP, 75012, Paris, France. bertrand.guidet@aphp.fr.ORCID http://orcid.org/0000-0002-7643-6770
Ariane Boumendilservice de réanimation, AP-HP, Hôpital Saint-Antoine, F75012, Paris, France.
Dylan W De LangeDepartment of Intensive Care Medicine, University Medical Center, University Utrecht, Utrecht, The Netherlands.
Susannah LeaverDepartment of Critical Care Medicine, St George's Hospital London, London, England.
Wojciech SzczeklikIntensive Care and Perioperative Medicine Division, Jagiellonian University Medical College, Kraków, Poland.
Christian JungDivision of Cardiology, Pulmonology and Vascular Medicine, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany.
Sigal SviriDepartment of Medical Intensive Care, Faculty of Medicine, Hebrew University and Hadassah University Medical Center, Jerusalem, Israel.
Michael BeilDepartment of Medical Intensive Care, Faculty of Medicine, Hebrew University and Hadassah University Medical Center, Jerusalem, Israel.
Hans FlaattenDepartment of Clinical Medicine, Department of Research and Developement, Haukeland University Hospital, University of Bergen, Bergen, Norway.
Hadassah Medical Center · ILInserm · FRDüsseldorf University Hospital · DEHaukeland University Hospital · NOJagiellonian University · PLSorbonne Université · FRSt George's Hospital · GBUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this narrative review, we describe the most important age-related "syndromes" found in the old ICU patients. The syndromes are frailty, comorbidity, cognitive decline, malnutrition, sarcopenia, loss of functional autonomy, immunosenescence and inflam-ageing. The underlying geriatric condition, together with the admission diagnosis and the acute severity contribute to the short-term, but also to the long-term prognosis. Besides mortality, functional status and quality of life are major outcome variables. The geriatric assessment is a key tool for long-term qualitative outcome, while immediate severity accounts for acute mortality. A poor functional baseline reduces the chances of a successful outcome following ICU. This review emphasises the importance of using a geriatric assessment and considering the older patient as a whole, rather than the acute illness in isolation, when making decisions regarding intensive care treatment.

Indexed as

Comprehensive geriatric assessmentCritical careIntensive care unitOld patients

Identifiers

PMID37542186
PMCPMC10403479
OpenAlexW4385575379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.