Evidence map›Paper›PMID 37542154›Full record

ArticleScientific reports2023

Artificial neural network approach for prediction of AuNPs biosynthesis by Streptomyces flavolimosus, characterization, antitumor potency in-vitro and in-vivo against Ehrlich ascites carcinoma.

Noura El-Ahmady El-Naggar, Nashwa H Rabei, Mohamed F Elmansy, Omar T Elmessiry, Mostafa K El-Sherbeny, Mohanad E El-Saidy, Mohamed T Sarhan, Manar G Helal

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. RSC advances · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Noura El-Ahmady El-NaggarDepartment of Bioprocess Development, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab City, 21934, Alexandria, Egypt. nouraalahmady@yahoo.com.ORCID http://orcid.org/0000-0001-8493-9194
Nashwa H RabeiDepartment of Bioprocess Development, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab City, 21934, Alexandria, Egypt.
Mohamed F ElmansyBiotechnology and Its Application Program, Department of Botany, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.
Omar T ElmessiryBiotechnology and Its Application Program, Department of Botany, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.
Mostafa K El-SherbenyBiotechnology and Its Application Program, Department of Botany, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.
Mohanad E El-SaidyBiotechnology and Its Application Program, Department of Botany, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.
Mohamed T SarhanBiotechnology and Its Application Program, Department of Botany, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt.
Manar G HelalDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) have emerged as promising and versatile nanoparticles for cancer therapy and are widely used in drug and gene delivery, biomedical imaging, diagnosis, and biosensors. The current study describes a biological-based strategy for AuNPs biosynthesis using the cell-free supernatant of Streptomyces flavolimosus. The biosynthesized AuNPs have an absorption peak at 530-535 nm. The TEM images indicate that AuNPs were spherical and ranged in size from 4 to 20 nm. The surface capping molecules of AuNPs are negatively charged, having a Zeta potential of - 10.9 mV. FTIR analysis revealed that the AuNPs surface composition contains a variety of functional groups as -OH, C-H, N-, C=O, NH

Indexed as

CarcinomaMetal NanoparticlesAnimalsAscitesGoldHeLa CellsHumansMiceStreptomycesGold

Identifiers

PMID37542154
PMCPMC10403537

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.