ArticleNature communications2023
A flexible optoacoustic blood 'stethoscope' for noninvasive multiparametric cardiovascular monitoring.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 57 citations in OpenAlex.
- Clinical applicable skin-interfaced thermal guiding sensor for warning perioperative abnormalities in core body temperature and blood perfusion rate.Nature communications · 2026Article
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- From intravascular imaging to adaptive vascular care: intelligent photonics and digital twins in panvascular disease.Light, science & applications · 2026Review
- Polymer-Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- 3D Large-Scale Subwavelength-Resolution Sound Sheet Tomography Based on an Active and Programmable Circular Meta-Array.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Wearable Flexible Sensors for Cardiovascular Disease Monitoring.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Flexible thermal array sensor for imperceptible monitoring of multidimensional vascular dynamics.Science advances · 2026Article
- Dynamic microvascular monitoring with miniaturized omnidirectional broadband photoacoustic imaging system for living entities (MOBILE).Nature communications · 2026Article
- Noninvasive Pulse Measurements for Cardiovascular Health Monitoring and Diagnoses.Advances in experimental medicine and biology · 2026Review
- State-of-the-art wearable sensors for cardiovascular health: a review.NPJ cardiovascular health · 2025Review
- Low-cost and compact second harmonic laser for photoacoustic imaging.Biomedical optics express · 2025Article
- Wearable Ultrasound Devices for Therapeutic Applications.Nano-micro letters · 2025Review
- Recent Progress in Blood Flow Sensing.Sensors and actuators. A, Physical · 2025Article
- Multiparametric super-resolution optoacoustic imaging with ICG-tagged microbubbles.Materials today. Bio · 2025Article
- Anti-Motion Artifacts Iontronic Sensor for Long-Term Accurate Fingertip Pulse Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Emerging Wearable Acoustic Sensing Technologies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- A Fully Integrated Orthodontic Aligner With Force Sensing Ability for Machine Learning-Assisted Diagnosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Enhancing image reconstruction in photoacoustic imaging using spatial coherence mean-to-standard-deviation factor beamforming.Biomedical optics express · 2024Article
- Advances in Wearable Biosensors for Healthcare: Current Trends, Applications, and Future Perspectives.Biosensors · 2024Review
- Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quantitative and multiparametric blood analysis is of great clinical importance in cardiovascular disease diagnosis. Although there are various methods to extract blood information, they often require invasive procedures, lack continuity, involve bulky instruments, or have complicated testing procedures. Flexible sensors can realize on-skin assessment of several vital signals, but generally exhibit limited function to monitor blood characteristics. Here, we report a flexible optoacoustic blood 'stethoscope' for noninvasive, multiparametric, and continuous cardiovascular monitoring, without requiring complicated procedures. The optoacoustic blood 'stethoscope' features the light delivery elements to illuminate blood and the piezoelectric acoustic elements to capture light-induced acoustic waves. We show that the optoacoustic blood 'stethoscope' can adhere to the skin for continuous and non-invasive in-situ monitoring of multiple cardiovascular biomarkers, including hypoxia, intravascular exogenous agent concentration decay, and hemodynamics, which can be further visualized with a tailored 3D algorithm. Demonstrations on both in-vivo animal trials and human subjects highlight the optoacoustic blood 'stethoscope''s potential for cardiovascular disease diagnosis and prediction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.