Evidence map›Paper›PMID 37541604›Full record

ArticleThe journal of pain2023

Real World Characterization of Chronic Pain, Success Rates and Implant Rates: Evidence from a Digital Health Platform of Patients Undergoing Spinal Cord Stimulation Evaluations.

Vishal Venkatraman, Rupinder Bharmi, Filippo Coletti, Ziad F Gellad, Noa Lempel, Roy Amit, Nicholas Blank, Jason Brown, Charisma Kumar, Michael Fishman and 6 more

Open access · hybridAbstract read
In one paragraph

Article in The journal of pain, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Vishal VenkatramanDepartment of Neurosurgery, Duke University School of Medicine, Durham, North Carolina.
Rupinder BharmiMedtronic Neuromodulation, Minneapolis, Minnesota.
Filippo ColettiStudy and Scientific Solutions, Medtronic, Rome, Italy.
Ziad F GelladDivision of Gastroenterology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Noa LempelNutrino Health, Medtronic, Tel Aviv, Israel.
Roy AmitNutrino Health, Medtronic, Tel Aviv, Israel.
Nicholas BlankMedtronic Neuromodulation, Minneapolis, Minnesota.
Jason BrownMedtronic Neuromodulation, Minneapolis, Minnesota.
Charisma KumarMedtronic Neuromodulation, Minneapolis, Minnesota.
Michael FishmanCenter for Interventional Pain and Spine, Exton, Pennsylvania.
Ricardo VallejoNational Spine and Pain Centers, Bloomington, Illinois.
Devin DattaThe Back Center, Melbourne, Florida.
Bryce B ReeveDepartment of Population Health Sciences, Duke University School of Medicine, Durham, North Carolina.
Krishnan ChakravarthyCoastal Pain and Spinal Diagnostics, San Diego, California; Department of Anesthesiology, UC San Diego School of Medicine, La Jolla, California.
Ashwini D SharanMedtronic Neuromodulation, Minneapolis, Minnesota.
Shivanand P LadDepartment of Neurosurgery, Duke University School of Medicine, Durham, North Carolina.
Medtronic (United States) · USDuke University · USInternational Spine, Pain & Performance · USMedtronic (Israel) · ILMedtronic (Italy) · ITUniversity of California San Diego · US

Funding

NRSA Training CoreTL1TR002555 · NCATS · DUKE UNIVERSITY · PI EDELMAN, DAVID · 2018 to 2022
$3.7M
NCATS NIH HHS TL1 TR002555
6 · The paper itself

Abstract

Spinal cord stimulation is an effective treatment for those experiencing chronic back and leg pain but requires a temporary evaluation period (SCSeval) before permanent implantation. We present real-world data from 7,000 patients who underwent SCSeval while utilizing a mobile digital health platform for education, feedback, and outcomes collection during their surgical journey. We analyzed preoperative patient demographics, characterized patient pain profiles using the patient-reported outcomes measurement information system-29 surveys, and calculated the rates of conversion from temporary to permanent spinal cord stimulation (SCS) implantation. Between August 1, 2021, and March 2, 2023, 7,000 patients (mean age 59.1, 59.6% female) underwent SCSeval procedures while utilizing a mobile application. Patients commonly experienced aching, sharp, stabbing, tingling, numb, and burning pain. Patients had tried multiple prior therapies and wanted to reduce their use of opioids and pain medications. Overall, 90.1% of the patients had a successful SCSeval, and 80.4% of those converted to permanent implant, with the highest rates among those who underwent SCSeval in a hospital setting. There was a significant improvement in all domains of pain as evaluated by pre and postoperative patient-reported outcomes measurement information system-29 surveys. This study supports the use of digital health technology as part of the SCS journey to improve the patient experience and allow for robust patient-reported outcomes collection. The overall rate of SCSeval to permanent SCS in our study of 72.4% was higher than national rates of 64%, suggesting that an app may allow clinicians to better quantify changes in chronic pain and provide more insight into choosing to implant SCS permanently. PERSPECTIVE: This article presents real-world evidence from a digital health platform for therapy education and outcomes collection from patients undergoing spinal cord stimulation evaluation procedures. Such tools could allow for better pain characterization and allow for more nuanced tracking of patient outcomes among those with chronic pain.

Indexed as

Chronic PainSpinal Cord StimulationAnalgesics, OpioidFemaleHumansMalePain ManagementSpinal CordTreatment OutcomeAnalgesics, OpioidChronic painDigital healthMobile appPatient-reported outcomesSpinal cord stimulation

Identifiers

PMID37541604
PMCPMC11225030
OpenAlexW4385478532

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.