Evidence map›Paper›PMID 37540483›Full record

ReviewJournal of community genetics2023

Genetic counseling in sickle cell disease: Insights from the Indian tribal population.

Pooja Aggarwal, Deepa Bhat

Open access · greenAbstract readReview
In one paragraph

Review in Journal of community genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pooja AggarwalDepartment of Anatomy, JSS Medical College, JSS Academy of Higher Education & Research, Mysore, Karnataka, India.ORCID http://orcid.org/0009-0009-4851-2949
Deepa BhatDepartment of Anatomy, JSS Medical College, JSS Academy of Higher Education & Research, Mysore, Karnataka, India. deepabhat@jssuni.edu.in.ORCID https://orcid.org/0000-0002-4928-1718
JSS Academy of Higher Education and Research · IN

Funding

DBT-Wellcome Trust India Alliance IA/CRC/20/1/600007Wellcome Trust
6 · The paper itself

Abstract

Sickle cell disease (SCD) is an inherited disorder of hemoglobin. With an overall prevalence of 4.3%, India is the second-largest hub of SCD after Africa. Genetic counseling (GC) is the most cost-effective intervention to reduce the burden of a genetic disease including SCD. Even though GC's role in reducing SCD birth prevalence is well established, it is still not incorporated into Indian national policy and is unavailable to most Indians approaching their marriageable age and childbirth. GC perception and efficacy have also not been explored yet among young adults, especially in Indian tribal communities. Counseling in these communities requires careful consideration of their socioeconomic, cultural, and ethical values. Community engagement with local tribes and healthcare infrastructure in a multitier approach is essential for an effective GC. This review aims to provide healthcare providers and genetic counselors with the essentials of GC in the prevention and management of SCD among tribal communities based on the author's counseling experience in South India.

Indexed as

Genetic counselingGuidelinesScreeningSickle cell diseaseTribal communities

Identifiers

PMID37540483
PMCPMC10444709
OpenAlexW4385564464

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.