ArticlePlant biotechnology journal2023
SmCSP4 from aphid saliva stimulates salicylic acid-mediated defence responses in wheat by interacting with transcription factor TaWKRY76.
Article in Plant biotechnology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- The insect effector CSPs activate an atypical plant TNL immune receptor.Plant cell reports · 2026Article
- Molecular and transcriptional regulation of plant defense responses to aphid infestation.Stress biology · 2026Review
- Novel effector HYPB1 of cotton bollworm (Helicoverpa armigera) inhibits biosynthesis of plant secondary metabolites and promotes feeding by targeting cotton dirigent protein GhDIR15.Journal of integrative plant biology · 2026Article
- The zig-zag model of molecular defense and counterdefense in plant-herbivore interactions.Planta · 2026Review
- Roles of the chemosensory protein RpCSP8 in reproduction and feeding behavior of sexual and non-sexual female of Rhopalosiphum padi.Insect science · 2026Article
- Molecular interface of plant-insect warfare: functions and applications of salivary effectors in piercing-sucking pests.Pest management science · 2026Review
- Plant-Aphid Interactions in Cereal Crops: Wheat Plant Defense and Aphid Saliva-Mediated Coevolutionary Arms Race.Insects · 2026Review
- Insects manipulate host nuclear trafficking and epigenetic regulation to facilitate herbivory.Nature communications · 2026Article
- Salicylic acid: a key natural foundation for next-generation plant defense stimulators.Pest management science · 2026Review
- A comprehensive review of physiological and molecular responses to stress of lilies (genusHorticulture research · 2026Article
- Dual role of benzoxazinoids in plant response to combined drought stress and aphid feeding.Plant biology (Stuttgart, Germany) · 2026Article
- Aphid effector Mp10 balances immune suppression and defence activation through EDS1-dependent modulation of plant DAMP responses.The New phytologist · 2025Article
- Tomato Spotted Wilt Virus Promotes Offspring and Egg Production of Its Vector, Frankliniella occidentalis, by Suppressing Plant Defences Induced by a Thrips Salivary Elicitor.Molecular plant pathology · 2025Article
- Review
- Diurnal rhythms in durum wheat triggered by Rhopalosiphum padi (bird cherry-oat aphid).BMC plant biology · 2025Article
- Review
- An odorant-binding protein functions in fire ant social immunity interfacing with innate immunity.Open biology · 2025Article
- PbrMYB14 Enhances Pear Resistance toInternational journal of molecular sciences · 2025Article
- Plant immunity to insect herbivores: mechanisms, interactions, and innovations for sustainable pest management.Frontiers in plant science · 2025Review
- Molecular Characterization of Chemosensory Protein (CSP) Genes and the Involvement ofInternational journal of molecular sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aphid salivary proteins are critical in modulating plant defence responses. Grain aphid Sitobion miscanthi is an important wheat pest worldwide. However, the molecular basis for the regulation of the plant resistance to cereal aphids remains largely unknown. Here, we show that SmCSP4, a chemosensory protein from S. miscanthi saliva, is secreted into wheat plants during aphid feeding. Delivery of SmCSP4 into wheat leaves activates salicylic acid (SA)-mediated plant defence responses and subsequently reduces aphid performance by deterring aphid feeding behaviour. In contrast, silencing SmCSP4 gene via nanocarrier-mediated RNAi significantly decreases the ability of aphids to activate SA defence pathway. Protein-protein interaction assays showed that SmCSP4 directly interacts with wheat transcriptional factor TaWRKY76 in plant nucleus. Furthermore, TaWRKY76 directly binds to the promoter of SA degradation gene Downy Mildew Resistant 6 (DMR6) and regulates its gene expression as transcriptional activator. SmCSP4 secreted by aphids reduces the transcriptional activation activity of TaWRKY76 on DMR6 gene expression, which is proposed to result in increases of SA accumulation and enhanced plant immunity. This study demonstrated that SmCSP4 acts as salivary elicitor that is involved in activating SA signalling defence pathway of wheat by interacting with TaWRKY76, which provide novel insights into aphid-cereal crops interactions and the molecular mechanism on induced plant immunity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.