Evidence map›Paper›PMID 37540347›Full record

ArticleJournal of ultrasound2023

The utility and tolerability of ultrasound guided muscle biopsy in the investigation of myopathy: a follow-up study.

Peter Connell, Woon Senn Koh, Frederick Vonberg, Stuart Viegas, Clara Limback-Stanic, Dimitri Amiras

Abstract read
In one paragraph

Article in Journal of ultrasound, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Updates in ultrasound-guided musculoskeletal interventions.The British journal of radiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Peter ConnellDepartment of Imaging, Imperial College Healthcare NHS Trust, London, UK. peter.connell1@nhs.net.ORCID http://orcid.org/0000-0002-3622-9144
Woon Senn KohDepartment of Neurology, Imperial College Healthcare NHS Trust, London, UK.
Frederick VonbergDepartment of Neurology, Imperial College Healthcare NHS Trust, London, UK.
Stuart ViegasDepartment of Neurology, Imperial College Healthcare NHS Trust, London, UK.
Clara Limback-StanicDepartment of Neuropathology, Oxford University Hospitals Instead of ICHNT, Oxford, UK.
Dimitri AmirasDepartment of Imaging, Imperial College Healthcare NHS Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOpen surgical muscle biopsy has traditionally been required for the histological diagnosis of myopathy but requires neurosurgical expertise with a variable diagnostic yield. Ultrasound guided percutaneous approaches are less resource intensive and invasive. This follow-up study aims to assess the diagnostic yield and tolerability of this approach to assess its utility as an adjunct to the traditional open surgical technique. METHODOLOGY: Between March of 2020 and June of 2021, 24 patients underwent a muscle biopsy following discussion at our regional neuromuscular multi-disciplinary team meeting. A consultant musculoskeletal radiologist used a modified Bergstrom needle to obtain a minimum of 2 samples under 500 mmHg of suction and ultrasound guidance. These were followed up to assess the diagnostic yield. A survey was also sent to the patients to assess the tolerability of the procedure.

results21 out of the 24 biopsies performed provided diagnostic information. Of these 3 non diagnostic samples were obtained, two were insufficient in size and one consisted of fatty tissue. Of the 21 patients who responded to the survey, 18 rated the procedure as good or excellent with 3 patients rated it as average or poor citing administrative or communication issues rather than procedural. All 5 patients who had previously undergone surgical biopsy expressed a preference for the ultrasound guided percutaneous approach. No patients experienced any complications.

conclusionThis follow-up study reinforces the conclusion of its predecessor by highlighting that ultrasound guided percutaneous muscle biopsy is a useful and tolerable adjunct to the traditional surgical technique in investigating muscle disorders.

Indexed as

Muscular DiseasesBiopsy, Fine-NeedleFollow-Up StudiesHumansImage-Guided BiopsyMusclesRetrospective StudiesUltrasonography, InterventionalBiopsyGuidedMuscleMyopathyUltrasound

Identifiers

PMID37540347
PMCPMC10632308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.