Evidence map›Paper›PMID 37540296›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023

Validation of the bowel urgency numeric rating scale in patients with Crohn's disease: results from a mixed methods study.

Marla C Dubinsky, Laure Delbecque, Theresa Hunter, Gale Harding, Larissa Stassek, Richard E Moses, James D Lewis

Open access · hybridAbstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Marla C DubinskyPediatric GI and Nutrition, Icahn School of Medicine- Mount Sinai Hospital, New York City, NY, USA.
Laure DelbecqueEli Lilly and Company, 893 Delaware St, Indianapolis, IN, 46225, USA.
Theresa HunterEli Lilly and Company, 893 Delaware St, Indianapolis, IN, 46225, USA. hunter_theresa_marie@lilly.com.ORCID http://orcid.org/0000-0001-8412-9175
Gale HardingEvidera, Bethesda, MD, USA.
Larissa StassekEvidera, Bethesda, MD, USA.
Richard E MosesEli Lilly and Company, 893 Delaware St, Indianapolis, IN, 46225, USA.
James D LewisPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Eli Lilly (United States) · USIthaka Harbors · USMount Sinai Hospital · USUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBowel urgency (BU) is an important symptom of Crohn's disease (CD), however there is no patient-reported outcome (PRO) scale validated in this population to assess BU severity. Here we evaluated the content validity and psychometric properties of the Urgency Numeric Rating Scale (NRS).

methodQualitative interviews were conducted with moderate-to-severe CD participants to confirm importance and relevance of BU in this population, cognitively debrief the Urgency NRS, and explore score interpretation and CD remission. A quantitative web survey study was conducted to explore the measurement properties of the urgency NRS.

resultsQualitative Interview: 34 of 35 participants reported BU. It was most bothersome for 44%, 47% reported it daily, 18% with every bowel movement. BU had a severe impact on daily activities, causing many participants to stay home more than preferred. Patients confirmed the relevance, appropriateness, comprehensibility of the item, recall period, response options, and instructions of the Urgency NRS. Small reductions on the Urgency NRS score reflected meaningful improvements. Quantitative survey: The study sample comprised 76 participants (65.8% female). Mean Urgency NRS score was 4.7 (SD 2.26; N = 76) at Week 1, with no floor/ceiling effect. Test-retest reliability was acceptable. Construct and known-groups validity against selected PROs were overall strong and within ranges hypothesized a priori.

conclusionThe Urgency NRS is a valid and reliable instrument to assess BU severity in CD.

Indexed as

Crohn DiseaseFemaleHumansMalePsychometricsQuality of LifeReproducibility of ResultsSeverity of Illness IndexSurveys and QuestionnairesBowel urgencyCrohn's diseaseNumeric rating scaleQualitative interviewsUrgency NRS

Identifiers

PMID37540296
PMCPMC10624712
OpenAlexW4385564709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.