Evidence map›Paper›PMID 37540271›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2023

Integrating US-guided FNAB, BRAF

Ning Ma, Hai-Ying Tian, Zhao-Yan Yu, Xin Zhu, Dai-Wei Zhao

Open access · hybridAbstract read
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ning MaClinical Medical College, Guizhou Medical University, Guiyang, China.
Hai-Ying TianClinical Medical College, Guizhou Medical University, Guiyang, China.
Zhao-Yan YuDepartment of Vascular and Thyroid Surgery, Guizhou Provincial People's Hospital, Guiyang, China.
Xin ZhuDepartment of Vascular and Thyroid Surgery, Guizhou Provincial People's Hospital, Guiyang, China.
Dai-Wei ZhaoClinical Medical College, Guizhou Medical University, Guiyang, China. zzhaodaiwei@hotmail.com.ORCID http://orcid.org/0009-0000-4668-7096
Guiyang Medical University · CNGuizhou Provincial People's Hospital · CN

Funding

Guizhou Provincial Science and Technology Projects ZK [2022] 257National Natural Science Foundation of China 81860478
6 · The paper itself

Abstract

backgroundThe prevalence of cervical central lymph-node metastasis (CLNM) is high in patients with papillary thyroid carcinoma (PTC). There is considerable controversy surrounding the benefits of prophylactic central lymph-node dissection (pCLND) in patients with clinically negative central compartment lymph nodes (cN0). Therefore, it is crucial to accurately predict the likelihood of cervical CLNM before surgery to make informed surgical decisions.

methodsDate from 214 PTC patients (cN0) who underwent partial or total thyroidectomy and pCLND at the Guizhou Provincial People's Hospital were collected and retrospectively analyzed. They were divided into two groups in accordance with cervical CLNM or not. Their information, including clinical characteristics, ultrasound (US) features, pathological results of fine-needle aspirations biopsy (FNAB), and other characteristics of the groups, was analyzed and compared using univariate and multivariate logistic regression analyses.

resultsA total of 214 patients were eligible in this study. Among them, 43.5% (93/214) of PTC patients had cervical CLNM, and 56.5% (121/214) did not. The two groups were compared using a univariate analyses, and there were no significant differences between the two groups in aspect ratio, boundary, morphology, component, and BRAF

conclusionsIn conclusion, four independent predictors of cervical CLNM, including age < 45 years, tumor size > 1.0 cm, capsule contact, and rich blood flow, were screened out. Therefore, a comprehensive assessment of these risk factors should be conducted when designing individualized treatment regimens for PTC patients.

Indexed as

Carcinoma, PapillaryThyroid NeoplasmsBiopsy, Fine-NeedleHumansLymphatic MetastasisLymph NodesMiddle AgedMutationProto-Oncogene Proteins B-rafRetrospective StudiesRisk FactorsThyroid Cancer, PapillaryBRAF protein, humanProto-Oncogene Proteins B-rafBRAFV600E mutationCentral lymph-node metastasisClinically negative central compartment lymph nodeFine-needle aspirations biopsyPapillary thyroid carcinomaProphylactic central lymph-node dissection

Identifiers

PMID37540271
PMCPMC10620286
OpenAlexW4385563785

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.