ArticleCerebral cortex (New York, N.Y. : 1991)2023
Brain functional characterization of response-code conflict in dual-tasking and its modulation by age.
Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 6 citations in OpenAlex.
- Multitasking Practice Eliminates Modality-Based Interference by Separating Task Representations in Sensory Brain Regions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Association between Inhibitory-Excitatory Balance and Brain Activity Response during Cognitive Flexibility in Young and Older Individuals.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Instrumental music training relates to intensity assessment but not emotional prosody recognition in Mandarin.PloS one · 2024Article
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Authors and funding
6 authors at 3 institutions in 1 country.
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Abstract
Crosstalk between conflicting response codes contributes to interference in dual-tasking, an effect exacerbated in advanced age. Here, we investigated (i) brain activity correlates of such response-code conflicts, (ii) activity modulations by individual dual-task performance and related cognitive abilities, (iii) task-modulated connectivity within the task network, and (iv) age-related differences in all these aspects. Young and older adults underwent fMRI while responding to the pitch of tones through spatially mapped speeded button presses with one or two hands concurrently. Using opposing stimulus-response mappings between hands, we induced conflict between simultaneously activated response codes. These response-code conflicts elicited activation in key regions of the multiple-demand network. While thalamic and parietal areas of the conflict-related network were modulated by attentional, working-memory and task-switching abilities, efficient conflict resolution in dual-tasking mainly relied on increasing supplementary motor activity. Older adults showed non-compensatory hyperactivity in left superior frontal gyrus, and higher right premotor activity was modulated by working-memory capacity. Finally, connectivity between premotor or parietal seed regions and the conflict-sensitive network was neither conflict-specific nor age-sensitive. Overall, resolving dual-task response-code conflict recruited substantial parts of the multiple-demand network, whose activity and coupling, however, were only little affected by individual differences in task performance or age.
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