Evidence map›Paper›PMID 37539871›Full record

ArticleJournal of neurosurgery. Case lessons2023

Pediatric intracranial tuberculoma: illustrative case.

Eva Liu, Pramath Kakodkar, Henry Pan, Amy Zhou, Patrick Toyota, Amit Rahul Persad, Kristen Marciniuk, Chunjie Wang, Roland Nikolaus Auer, Stephen Sanche and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Eva LiuDepartments of1Neurosurgery.
Pramath Kakodkar2Pathology and Laboratory Medicine, and.
Henry Pan2Pathology and Laboratory Medicine, and.
Amy ZhouDepartments of1Neurosurgery.
Patrick ToyotaDepartments of1Neurosurgery.
Amit Rahul PersadDepartments of1Neurosurgery.
Kristen MarciniukDepartments of1Neurosurgery.
Chunjie Wang2Pathology and Laboratory Medicine, and.
Roland Nikolaus Auer2Pathology and Laboratory Medicine, and.
Stephen Sanche3Infectious Disease, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Aleksander VitaliDepartments of1Neurosurgery.
Julia RadicDepartments of1Neurosurgery.
University of Saskatchewan · CAEmory University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis is an airborne disease caused by Mycobacterium tuberculosis. Intracranial tuberculoma is a rare complication of extrapulmonary tuberculosis due to hematogenous spread to subpial and subependymal regions. Intracranial tuberculoma can occur with or without meningitis. OBSERVATIONS: A 3-year-old male who had recently emigrated from Sudan presented to the emergency department with right-sided seizures lasting 30 minutes, which were aborted with levetiracetam and midazolam. Head computed tomography revealed a multilobulated left supratentorial mass with solid and cystic components and measuring 8.0 × 4.8 × 6.5 cm. The patient had successful resection of the mass, which was positive for M. tuberculosis. He was started on rifampin, isoniazid, pyrazinamide, ethambutol, and fluoroquinolone and was discharged home in stable condition. LESSONS: A literature review on pediatric intracranial tuberculoma was performed, which included 48 studies (n = 49). The mean age was 8.8 ± 5.4 years with a slight female predilection (59%). Predominant solitary tuberculomas (63%) were preferentially managed with both resection and antituberculosis therapy (ATT), whereas multifocal tuberculomas were preferentially managed with ATT. Intracranial tuberculoma is a rare but treatable cause of space-occupying lesions in children. Clinicians should maintain a high level of suspicion in patients from endemic regions and involve the infectious disease service early.

Indexed as

extrapulmonary tuberculosisinfectious diseaseintracranial tuberculomapediatric

Identifiers

PMID37539871
PMCPMC10555599
OpenAlexW4385240772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.