Evidence map›Paper›PMID 37539226›Full record

ArticleHeliyon2023

Inhibition of microRNA-122 alleviates pyroptosis by targeting dual-specificity phosphatase 4 in myocardial ischemia/reperfusion injury.

Hongjin Wu, Qiang Fu, Zhong Li, Huamin Wei, Shuyan Qin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Unveiling the 'Eating Poison' ofJournal of pharmaceutical analysis · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Hongjin WuBoao International Hospital, Shanghai University of Traditional Chinese Medicine, Hainan 571437, China.
Qiang FuDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Zhong LiDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Huamin WeiDepartment of Traditional Chinese Medicine, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Shuyan QinDepartment of Cardiology, Nanyang Second General Hospital, Henan 473000, China.
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNCapital Medical University · CNSecond Hospital of Nanchang · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyroptosis is a type of programmed cell death that induces myocardial ischemia-reperfusion injury (I/RI), which leads to cardiac dysfunction and even lethal reperfusion injury. MiR-122 is a liver-specific miRNA associated with coronary heart disease, but its role in pyroptosis activation in myocardial I/RI remains unclear. Thus, this study aimed to determine whether miR-122 inhibition exerts myocardial I/RI protection in

Indexed as

DUSP4miR-122Myocardial ischemia/reperfusion injuryPyroptosis

Identifiers

PMID37539226
PMCPMC10393637
OpenAlexW4384133399

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.