Evidence map›Paper›PMID 37539048›Full record

ArticleFrontiers in immunology2023

Microenvironmental and cell intrinsic factors governing human cDC2 differentiation and monocyte reprogramming.

Magdalena Lang, Corinna Krump, Anastasia Meshcheryakova, Carmen Tam-Amersdorfer, Elke Schwarzenberger, Christina Passegger, Sally Connolly, Diana Mechtcheriakova, Herbert Strobl

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Type 2 immunity in allergic diseases.Cellular & molecular immunology · 2025
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Magdalena LangDivision of Immunology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Corinna KrumpDivision of Immunology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Anastasia MeshcheryakovaInsitute of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Carmen Tam-AmersdorferDivision of Immunology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Elke SchwarzenbergerDivision of Immunology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Christina PasseggerDivision of Immunology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Sally ConnollyDivision of Immunology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Diana MechtcheriakovaInsitute of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Herbert StroblDivision of Immunology, Otto Loewi Research Center, Medical University of Graz, Graz, Austria.
Medical University of Graz · ATMedical University of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

cDC2s occur abundantly in peripheral tissues and arise from circulating blood cDC2s. However, the factors governing cDC2 differentiation in tissues, especially under inflammatory conditions, remained poorly defined. We here found that psoriatic cDC2s express the efferocytosis receptor Axl and exhibit a bone morphogenetic protein (BMP) and p38MAPK signaling signature. BMP7, strongly expressed within the lesional psoriatic epidermis, cooperates with canonical TGF-β1 signaling for inducing Axl

Indexed as

Dendritic CellsMonocytesCell DifferentiationEpidermisHumansSkindendritic cellepidermal signalinginflammatory skin diseaseLangerhans celllineage decisiontranscriptional reprogramming

Identifiers

PMID37539048
PMCPMC10395083
OpenAlexW4384823046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.