Evidence map›Paper›PMID 37538752›Full record

ArticleTurkish journal of chemistry2022

Synthesis and investigation of antiproliferative activity of Ru-NHC complexes against C6 and HeLa cancer cells.

Ramazan Paşahan, Mitat Akkoç, Şeyma Yaşar, Tuğba Kul Köprülü, Şaban Tekin, Sedat Yaşar, İsmail Özdemir

Open access · greenAbstract read
In one paragraph

Article in Turkish journal of chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Biological Activities of Ruthenium NHC Complexes: An Update.Antibiotics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ramazan PaşahanDepartment of Neurosurgery,, Faculty of Medicine, İnönü University, Malatya, Turkey.ORCID https://orcid.org/0000-0002-3221-1422
Mitat AkkoçDepartment of Property Protection and Security, Hekimhan Vocational College, Malatya Turgut Özal University, Malatya, Turkey.ORCID https://orcid.org/0000-0001-8641-8958
Şeyma YaşarDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, İnönü University, Malatya, Turkey.ORCID https://orcid.org/0000-0003-1300-3393
Tuğba Kul KöprülüExperimental Medicine Application and Research Center, University of Health Sciences, İstanbul, Turkey.ORCID https://orcid.org/0000-0001-9451-5715
Şaban TekinExperimental Medicine Application and Research Center, University of Health Sciences, İstanbul, Turkey.ORCID https://orcid.org/0000-0003-2641-6293
Sedat YaşarDepartment of Chemistry, Faculty of Science and Arts, İnönü University, Malatya, Turkey.ORCID https://orcid.org/0000-0001-7285-2761
İsmail ÖzdemirDepartment of Neurosurgery,, Faculty of Medicine, İnönü University, Malatya, Turkey.ORCID https://orcid.org/0000-0001-6325-0216
Inonu University · TRIstanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2-methylpyridine, 2-diethylaminoethyl, and isopentyl linked a series of symmetric and unsymmetric benzimidazolium salts 2a-e were prepared and used in the synthesis of silver-N-heterocyclic carbene (NHC) complexes (3a-e). The Ru(II)-NHC complexes (4a-h) were synthesized via transmetalation reaction from 3a-e. 4a-h complexes were converted to Ru(II)-NHC.HCl complexes (5ah) by HCl solution of diethyl ether and characterized by different spectroscopic techniques such as

Indexed as

antiproliferative activityC6HeLaN-heterocyclic carbenerutheniumsilver

Identifiers

PMID37538752
PMCPMC10395682
OpenAlexW4290005300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.