Evidence map›Paper›PMID 37538350›Full record

ArticleSaudi journal of biological sciences2023

Protective roles of vitamin C and 5-aminosalicylic acid on reproduction in acrylamide intoxicated male mice.

Md Eftakhar Jahan Bhuiyan, Md Golzar Hossain, Amit Saha, Md Kamrul Islam, Farida Yeasmin Bari, Md Abu Hadi Noor Ali Khan, Sharmin Akter

Open access · hybridAbstract read
In one paragraph

Article in Saudi journal of biological sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Md Eftakhar Jahan BhuiyanDepartment of Physiology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Md Golzar HossainDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Amit SahaDepartment of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Md Kamrul IslamDepartment of Physiology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Farida Yeasmin BariDepartment of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Md Abu Hadi Noor Ali KhanDepartment of Pathology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Sharmin AkterDepartment of Physiology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh.
Bangladesh Agricultural University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Serious health risks have been connected to ongoing, escalating exposure to environmental toxins and one of them is acrylamide (ACR), an organic compound. Although there are many published reports on ACR toxicity, limited information is available regarding the use of two potential antioxidants against ACR-instigated reproductive toxicity. Aims: The study focused on investigating the protective effects of vitamin C and 5-ASA against ACR-incited reproductive toxicity. Methods: A total of 50 male mice aged 4 weeks old were treated for 90 days with different concentrations either of ACR or ACR and vitamin C or ACR and 5- ASA or ACR, vitamin C, and 5- ASA. Key results: ACR significantly reduced serum testosterone level ( Conclusions: Vitamin C and 5-ASA can potentially mitigate the negative effects of ACR on male reproduction; however, combined application is recommended for better performance. Implications: In Bangladesh, this work is anticipated to address the health benefits of vitamin C and 5-ASA, particularly in improving the reproductive health of males against ACR toxicity.

Indexed as

AcrylamideAntioxidantsEpididymisSpermTestisToxicity

Identifiers

PMID37538350
PMCPMC10393805
OpenAlexW4384207818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.