Evidence map›Paper›PMID 37538303›Full record

ArticleFrontiers in fungal biology2023

Cell wall composition in

Rajendra Upadhya, Woei C Lam, Camaron R Hole, Joseph G Vasselli, Jennifer K Lodge

Open access · goldAbstract read
In one paragraph

Article in Frontiers in fungal biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  3. Acetylation and accessibility ofCell surface (Amsterdam, Netherlands) · 2026
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  4. Molecular Architecture ofbioRxiv : the preprint server for biology · 2026
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  6. Review
  7. Mitochondrial cardiolipin sequestration of caspofungin underliesbioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Lack of an atypical PDR transporter generates an immunogenicbioRxiv : the preprint server for biology · 2025
    Article
  17. On-Resin Assembly of Macrocyclic Inhibitors ofJournal of medicinal chemistry · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rajendra UpadhyaDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, United States.
Woei C LamDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, United States.
Camaron R HoleDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, United States.
Joseph G VasselliDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, United States.
Jennifer K LodgeDepartment of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, United States.
Duke University · USWashington University in St. Louis · US

Funding

Preclinical studies of a Cryptococcus vaccine for AIDS patientsR01AI125045 · NIAID · WASHINGTON UNIVERSITY · PI LEVITZ, STUART MICHAEL, LODGE, JENNIFER K. · 2016 to 2025
$7.1M
Chitosan in CryptococcusR01AI072195 · NIAID · WASHINGTON UNIVERSITY · PI LODGE, JENNIFER K. · 2008 to 2018
$3.5M
NIAID NIH HHS R01 AI072195NIAID NIH HHS R01 AI125045
6 · The paper itself

Abstract

Introduction: Objective: The purpose of this study was to determine how different media influenced the amount of chitin and chitosan in the cell wall, which in turn impacted the cell wall architecture and host response. Methods: Yeast extract, peptone, and dextrose (YPD) and yeast nitrogen base (YNB) are two commonly used media for growing Cryptococcus before use in in vitro or in vivo experiments. As a result, Results: We observed that the growth of wild-type Conclusion: These findings emphasize the importance of culture media and pH during growth in shaping the content and organization of the

Indexed as

cell wallchitin deacetylasechitosanCryptococcusfungal PAMPsfungal virulenceYNB medium

Identifiers

PMID37538303
PMCPMC10399910
OpenAlexW4376279985

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.