Evidence map›Paper›PMID 37538290›Full record

ArticlePrzeglad gastroenterologiczny2023

Study of the gut microbiome in Egyptian patients with type 1 diabetes mellitus.

Ahmed I Allakany, Amany A Elbanna, Kamel H Rohoma, Shwikar M Ahmed, Ahmed E Ibrahim, Moamen A Fawzy, Doaa A Header

Open access · goldAbstract read
In one paragraph

Article in Przeglad gastroenterologiczny, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. T-Cell Receptor Sequences Identify Combined Coxsackievirus-International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ahmed I AllakanyDepartment of Internal Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Amany A ElbannaDepartment of Internal Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Kamel H RohomaDepartment of Internal Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Shwikar M AhmedDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Ahmed E IbrahimDepartment of Neuropsychiatry, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Moamen A FawzyDepartment of Internal Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Doaa A HeaderDepartment of Internal Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Alexandria University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Type 1 diabetes mellitus (T1DM) is an autoimmune disease. The gut microbiota has been proposed as a key actor in the pathogenesis of T1DM. Aim: To identify the gut microbiome that are likely to be related to T1DM. This may have an impact on the future understanding of the pathogenesis of T1DM and possible approaches to prevent and treat it. Material and methods: The study included 40 T1DM patients and a cross-matching control group of 20 healthy subjects of matched age and sex; stool specimens were taken from each group. Quantitative SYBR Green Real-Time PCR technique targeting 16S rRNA was done for the identification and quantitation of Results: T1DM patients showed significantly higher Conclusions: Egyptian patients showed dysbiosis of the gut microbiome that can be related to the pathogenesis of T1DM. This hopefully points to the potential therapeutic benefits of manipulating the composition of the gut microbiome in the management of, or even protection from, T1DM.

Indexed as

dysbiosisgut microbiomereal-time polymerase chain reactiontype 1 diabetes mellitus

Identifiers

PMID37538290
PMCPMC10395059
OpenAlexW4361771482

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.