Freeze-fracture cytochemistry of wheat germ agglutinin and concanavalin A receptors on the plasma membrane of normal, Bernard-Soulier, and thrombasthenic platelets.

J Chevalier, J P Caen, P Pinto da Silva

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In one paragraph

Article in The American journal of pathology, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

1.4field-weighted citation impact, top 21% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Distribution of glycoconjugates on the plasma membrane and on membranes of the open-canalicular system in human platelets. A cytochemical study.Histochemistry · 1989
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J Chevalier

J P Caen

P Pinto da Silva

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors report here the results of fracture-labeling of wheat germ agglutinin (WGA) and concanavalin A (Con A) receptors on the plasma membranes of normal, Bernard-Soulier, and thrombasthenic platelets. In all cases, virtually all of the label was confined to the exoplasmic half of the membrane. Despite the absence of GP Ib in Bernard-Soulier platelets and the absence or strong reduction of Gp IIb and GP IIIa in thrombasthenic platelets, their plasma membranes were strongly labeled by both Con A and WGA. These results are best accounted for by the presence of other glycoproteins and/or glycolipids at the platelet surface.

Indexed as

AdultBernard-Soulier SyndromeBlood Platelet DisordersBlood PlateletsCell MembraneConcanavalin AFreeze FracturingGlycoproteinsHistocytochemistryHumansLectinsMicroscopy, ElectronReceptors, Concanavalin AReceptors, MitogenThrombastheniaWheat Germ AgglutininsConcanavalin AGlycoproteinsLectinsReceptors, Concanavalin AReceptors, Mitogenwheat germ agglutinin receptorWheat Germ Agglutinins

Identifiers

PMID3753826

PMCPMC1888117

OpenAlexW178018575

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.