Evidence map›Paper›PMID 37537560›Full record

ReviewLipids in health and disease2023

Etiological relationship between lipid metabolism and endometrial carcinoma.

Wenzhe Li, Yi Xu, Xinling Zeng, Jie Tan, Ya Wang, Hongyan Wu, Maokun Li, Cunjian Yi

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lipids in health and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wenzhe Li *Department of Endocrinology, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, China.
Yi Xu *Department of Endocrinology, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, China.
Xinling Zeng *Department of Gynecology and Obstetrics, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, China.
Jie TanDepartment of Hematology, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, China.
Ya WangDepartment of Endocrinology, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, China. wangya@yangtzeu.edu.cn.
Hongyan WuDepartment of Endocrinology, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, China.
Maokun LiDepartment of Hubei Provincial Clinical Research Center for Personalized Diagnosis and Treatment of Cancer, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, China. maokunli09@126.com.
Cunjian YiDepartment of Gynecology and Obstetrics, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei, China. cunjiany@yangtzeu.edu.cn.
Yangtze University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial carcinoma (EC) has become one of the most common gynecological malignant neoplasms in developed countries worldwide. Studies have shown that this may be closely related to the abnormal metabolism of blood lipids, which was the most significant metabolic change in the human body in this cancer. In this review, we focus on the correlation between lipid metabolism and EC and discuss the evidence that abnormal lipid metabolism promotes an increase in EC growth and metabolism, as well as the regulatory mechanism and related signaling pathways involved in this relationship. In addition, we also discussed the research progress of targeted therapies and drug treatments for EC that act on lipid metabolism, and statins are expected to become adjuvant drugs for EC in the future. This review will provide a systematic view for a better understanding of the etiological relationship between lipid metabolism and EC and further open up new therapeutic possibilities and effective treatments for EC by targeting lipid metabolism.

Indexed as

Endometrial NeoplasmsLipid MetabolismFemaleHumansSignal TransductionBiological mechanismsEndometrial carcinomaEtiological relationshipLipid metabolismStatins

Identifiers

PMID37537560
PMCPMC10401764
OpenAlexW4385519612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.