ArticleNature biomedical engineering2023
Soft and stretchable organic bioelectronics for continuous intraoperative neurophysiological monitoring during microsurgery.
Article in Nature biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 45 citations in OpenAlex.
- A soft bioelectronic system with a responsive hydrogel neural interface for direct force quantification and real-time intraoperative craniocerebral injury monitoring.Nature biomedical engineering · 2026Article
- Mechanically Compliant, Precision-Porous Brain Implants Reduce the Foreign Body Reaction and Guide Regeneration.Advanced healthcare materials · 2026Article
- PEDOT: PSS for Implantable and Wearable Bioelectronics: From Material Engineering and Energy Storage to Clinical Translation.Small (Weinheim an der Bergstrasse, Germany) · 2026Review
- Ion-shielding ultrathin encapsulation with hot-press bonded interface enables chronic stretchable bioelectronics.Science advances · 2026Article
- Ionic-Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Bioadhesive and conformable bioelectronic interfaces for vasomotoricity monitoring and regulation.Nature communications · 2025Article
- Soft Bioelectronic Interfaces for Continuous Peripheral Neural Signal Recording and Robust Cross-Subject Decoding.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Enhanced laser-induced PEDOT-based hydrogels for highly conductive bioelectronics.National science review · 2025Article
- An ICU-grade breathable cardiac electronic skin for health, diagnostics, and intraoperative and postoperative monitoring.Science advances · 2025Article
- Evaporative Morphology Tuning of Conducting Polymer Films Under Controlled Vacuum Conditions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Symmetry engineering in 2D bioelectronics facilitating augmented biosensing interfaces.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Electrochemically actuated microelectrodes for minimally invasive peripheral nerve interfaces.Nature materials · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 5 institutions in 2 countries.
Funding
Abstract
In microneurosurgery, it is crucial to maintain the structural and functional integrity of the nerve through continuous intraoperative identification of neural anatomy. To this end, here we report the development of a translatable system leveraging soft and stretchable organic-electronic materials for continuous intraoperative neurophysiological monitoring. The system uses conducting polymer electrodes with low impedance and low modulus to record near-field action potentials continuously during microsurgeries, offers higher signal-to-noise ratios and reduced invasiveness when compared with handheld clinical probes for intraoperative neurophysiological monitoring and can be multiplexed, allowing for the precise localization of the target nerve in the absence of anatomical landmarks. Compared with commercial metal electrodes, the neurophysiological monitoring system allowed for enhanced post-operative prognoses after tumour-resection surgeries in rats. Continuous recording of near-field action potentials during microsurgeries may allow for the precise identification of neural anatomy through the entire procedure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.