Evidence map›Paper›PMID 37537266›Full record

ArticleScientific reports2023

Label-free measurement of antimicrobial peptide interactions with lipid vesicles and nanodiscs using microscale thermophoresis.

Philip Rainsford, Fredrik G Rylandsholm, Martin Jakubec, Mitchell Silk, Eric Juskewitz, Johanna U Ericson, John-Sigurd Svendsen, Richard A Engh, Johan Isaksson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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  4. The antimicrobial activity of ETD151 defensin is dictated by the presence of glycosphingolipids in the targeted organisms.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Philip RainsfordDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019, Tromsø, Norway.
Fredrik G RylandsholmDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019, Tromsø, Norway.
Martin JakubecDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019, Tromsø, Norway.
Mitchell SilkDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019, Tromsø, Norway.
Eric JuskewitzResearch Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, UiT the Arctic University of Norway, 9019, Tromsø, Norway.
Johanna U EricsonResearch Group for Host Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, UiT the Arctic University of Norway, 9019, Tromsø, Norway.
John-Sigurd SvendsenDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019, Tromsø, Norway.
Richard A EnghDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019, Tromsø, Norway.
Johan IsakssonDepartment of Chemistry, Faculty of Science and Technology, UiT the Arctic University of Norway, 9019, Tromsø, Norway. johan.isaksson@uit.no.
UiT The Arctic University of Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One strategy to combat antimicrobial resistance is the discovery of new classes of antibiotics. Most antibiotics will at some point interact with the bacterial membrane to either interfere with its integrity or to cross it. Reliable and efficient tools for determining the dissociation constant for membrane binding (K

Indexed as

Antimicrobial PeptidesEscherichia coliLipidsStaphylococcus aureusStyreneAntimicrobial PeptidesLipidsStyrene

Identifiers

PMID37537266
PMCPMC10400562
OpenAlexW4385502397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.