Evidence map›Paper›PMID 37537116›Full record

ReviewSeminars in cell & developmental biology2024

Development and regeneration of the vagus nerve.

Adam J Isabella, Cecilia B Moens

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Pharmaceutical biology · 2026
    Review
  2. Review
  3. The critical role of gut-brain signalling in eating behaviour and obesity.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Adam J IsabellaDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: aisabell@umn.edu.
Cecilia B MoensBasic Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA. Electronic address: cmoens@fredhutch.org.
Fred Hutch Cancer Center · USUniversity of Minnesota · US

Funding

Topographic mapping by cranial motor neurons - Renewal - Resubmission - 1R01NS109425 · NINDS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Cecilia B Moens · 2018 to 2026
$2.9M
Mechanisms of Target-Specific Axon RegenerationR00NS121595 · NINDS · UNIVERSITY OF MINNESOTA · PI ISABELLA, ADAM JAMES · 2023 to 2025
$715k
Discovery of sensorimotor connectivity mechanisms in a continuous topographic mapR21NS124191 · NINDS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MOENS, CECILIA B · 2022 to 2023
$493k
Mechanisms of Target-Specific Axon RegenerationK99NS121595 · NINDS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ISABELLA, ADAM JAMES · 2022 to 2023
$176k
NINDS NIH HHS K99 NS121595NINDS NIH HHS R00 NS121595NINDS NIH HHS R01 NS109425NINDS NIH HHS R21 NS124191
6 · The paper itself

Abstract

The vagus nerve, with its myriad constituent axon branches and innervation targets, has long been a model of anatomical complexity in the nervous system. The branched architecture of the vagus nerve is now appreciated to be highly organized around the topographic and/or molecular identities of the neurons that innervate each target tissue. However, we are only just beginning to understand the developmental mechanisms by which heterogeneous vagus neuron identity is specified, patterned, and used to guide the axons of particular neurons to particular targets. Here, we summarize our current understanding of the complex topographic and molecular organization of the vagus nerve, the developmental basis of neuron specification and patterned axon guidance that supports this organization, and the regenerative mechanisms that promote, or inhibit, the restoration of vagus nerve organization after nerve damage. Finally, we highlight key unanswered questions in these areas and discuss potential strategies to address these questions.

Indexed as

AxonsNeuronsNerve RegenerationVagus NerveAxon guidanceIdentityNerve developmentNerve regenerationParasympatheticSpecificationVagus

Identifiers

PMID37537116
PMCPMC10830892
OpenAlexW4385456165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.