Evidence map›Paper›PMID 37535942›Full record

ArticleInorganic chemistry2023

Phototoxicity of Tridentate Ru(II) Polypyridyl Complex with Expanded Bite Angles toward Mammalian Cells and Multicellular Tumor Spheroids.

Rhianne C Curley, Christopher S Burke, Karmel S Gkika, Sara Noorani, Naomi Walsh, Tia E Keyes

Abstract read
In one paragraph

Article in Inorganic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Cell viability imaging in tumor spheroidsChemical communications (Cambridge, England) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rhianne C CurleySchool of Chemical Sciences and National Centre for Sensor Research, Dublin City University, Dublin 9 D09 NA55, Ireland.
Christopher S BurkeSchool of Chemical Sciences and National Centre for Sensor Research, Dublin City University, Dublin 9 D09 NA55, Ireland.
Karmel S GkikaSchool of Chemical Sciences and National Centre for Sensor Research, Dublin City University, Dublin 9 D09 NA55, Ireland.
Sara NooraniNational Institute for Cellular Biotechnology, School of Biotechnology, Dublin City University, Dublin 9 D09 NA55, Ireland.
Naomi WalshNational Institute for Cellular Biotechnology, School of Biotechnology, Dublin City University, Dublin 9 D09 NA55, Ireland.
Tia E KeyesSchool of Chemical Sciences and National Centre for Sensor Research, Dublin City University, Dublin 9 D09 NA55, Ireland.ORCID 0000-0002-4604-5533

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tridentate ligand-coordinated ruthenium (II) polypyridyl complexes with large N-Ru-N bite angles have been shown to promote ligand field splitting and reduce singlet-triplet state mixing leading to dramatically extended emission quantum yields and lifetimes under ambient conditions. These effects are anticipated to enhance their photoinduced singlet oxygen production, promoting prospects for such complexes as type II phototherapeutics. In this contribution, we examined this putative effect for [Ru(bqp)(bqpCOOEt)]

Indexed as

Coordination ComplexesNeoplasmsPhotochemotherapyRutheniumAnimalsCHO CellsCricetinaeCricetulusHumansLigandsPhotosensitizing AgentsCoordination ComplexesLigandsPhotosensitizing AgentsRuthenium

Identifiers

PMID37535942
PMCPMC10428208

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.