Evidence map›Paper›PMID 37535731›Full record

ArticleScience (New York, N.Y.)2023

Photosensitized O

Dhruba P Poudel, Amrit Pokhrel, Raj Kumar Tak, Majji Shankar, Ramesh Giri

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Rh-Catalyzed Enantioselective Aryl C-H Bond Cyclopropylation.Journal of the American Chemical Society · 2025
    Article
  7. Article
  8. Organophotocatalyst Enabled Deoxycyclopropanation of Alcohols.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Article
  10. Journal of the American Chemical Society · 2024
    Article
  11. Redox Approaches to Carbene Generation in Catalytic Cyclopropanation Reactions.Angewandte Chemie (International ed. in English) · 2024
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dhruba P PoudelDepartment of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0001-8948-4344
Amrit Pokhrel *Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-7432-8311
Raj Kumar Tak *Department of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0003-3726-8687
Majji ShankarDepartment of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.
Ramesh GiriDepartment of Chemistry, The Pennsylvania State University, University Park, PA 16802, USA.ORCID 0000-0002-8993-9131

Funding

New Directions in Alkene Difunctionalization ReactionsR35GM133438 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Ramesh Giri · 2019 to 2026
$3.2M
X-ray instrumentation upgrade for single crystal diffraction and solution small angle scatteringS10OD028589 · OD · PENNSYLVANIA STATE UNIVERSITY, THE · PI YENNAWAR, NEELA H. · 2020 to 2020
$600k
Macromolecular X-Ray Crystallography InstrumentS10RR023439 · NCRR · PENNSYLVANIA STATE UNIVERSITY, THE · PI YENNAWAR, NEELA H. · 2007 to 2007
$500k
NCRR NIH HHS S10 RR023439NIGMS NIH HHS R35 GM133438NIH HHS S10 OD028589
6 · The paper itself

Abstract

Cyclopropanes are key features in many preclinical, clinical, and commercial drugs, as well as natural products. The most prolific technique for their synthesis is the metal-catalyzed reaction of an alkene with a diazoalkane, a highly energetic reagent requiring stringent safety precautions. Discovery of alternative innocuous reagents remains an ongoing challenge. Herein, we report a simple photoredox-catalyzed intermolecular cyclopropanation of unactivated alkenes with active methylene compounds. The reaction proceeds in neutral solvent under air or dioxygen (O

Identifiers

PMID37535731
PMCPMC11216814

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.