Evidence map›Paper›PMID 37534445›Full record

ReviewDeutsches Arzteblatt international2023

Meralgia Paresthetica: Relevance, Diagnosis, and Treatment.

Christoph Scholz, Marc Hohenhaus, Maria T Pedro, Anne-Kathrin Uerschels, Nora F Dengler

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Deutsches Arzteblatt international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06251882 (6-month Efficacy of Ultrasound-guided Injection of 5% Dextrose for Meralgia Paresthesia), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06251882 nacompletednot on this map

6-month Efficacy of Ultrasound-guided Injection of 5% Dextrose for Meralgia Paresthesia

TypeinterventionalSponsorPeking University People's HospitalRan2022 to 2024Enrolled40ConditionsMeralgia ParestheticaArmsinjection
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Meralgia Paresthetica in a Patient with Hemophilia A.Internal medicine (Tokyo, Japan) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Meralgia paraesthetica.BJA education · 2025
    Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christoph ScholzDepartment of Neurosurgery, University Hospital Freiburg, Faculty of Medicine, University of Freiburg; Department of Neurosurgery, Peripheral Nerves Section, University of Ulm at Günzburg District Hospital; Department of Neurosurgery and Spinal Surgery, University Medical Center Essen; Department of Neurosurgery, Charité-University Medical Center Berlin.
Marc Hohenhaus
Maria T Pedro
Anne-Kathrin Uerschels
Nora F Dengler
University Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPain and sensory disturbance in the distribution of the lateral femoral cutaneous nerve in the ventrolateral portion of the thigh is called meralgia paresthetica (MP). The incidence of MP has risen along with the increasing prevalence of obesity and diabetes mellitus and was recently estimated at 32 new cases per 100 000 persons per year. In this review, we provide an overview of current standards and developments in the diagnosis and treatment of MP.

methodsThis review is based on publications retrieved by a selective literature search, with special attention to meta-analyses, systematic reviews, randomized and controlled trials (RCTs), and prospective observational studies.

resultsThe diagnosis is mainly based on typical symptoms combined with a positive response to an infiltration procedure. In atypical cases, electrophysiological testing, neurosonography, and magnetic resonance imaging can be helpful in establishing the diagnosis. The literature search did not reveal any studies of high quality. Four prospective observational studies with small case numbers and partly inconsistent results are available. In a meta-analysis of 149 cases, pain relief was described after infiltration in 85% of cases and after surgery in 80%, with 1-38 months of follow-up. In another meta-analysis of 670 cases, there was pain relief after infiltration in 22% of cases, after surgical decompression in 63%, and after neurectomy in 85%. Hardly any data are available on more recent treatment options, such as radiofrequency therapy, spinal cord stimulation, or peripheral nerve stimulation.

conclusionThe state of the evidence is limited in both quantity and quality, corresponding to evidence level 2a for surgical and non-surgical methods. Advances in imaging and neurophysiological testing have made the diagnosis easier to establish. When intervention is needed, good success rates have been achieved with surgery (decompression, neurectomy), and variable success rates with infiltration.

Indexed as

Femoral NeuropathyNerve Compression SyndromesDecompression, SurgicalHumansObservational Studies as TopicPainThigh

Identifiers

PMID37534445
PMCPMC10622057
OpenAlexW4385514653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.